9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione

Names

[ CAS No. ]:
84082-03-1

[ Name ]:
9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione

[Synonym ]:
4-demethoxy-6-deoxydaunorubicin
4-Demethoxy-4-iso-propoxy-daunorubicin*HCl

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
739.5ºC at 760 mmHg

[ Molecular Formula ]:
C26H27NO8

[ Molecular Weight ]:
481.49400

[ Flash Point ]:
401ºC

[ Exact Mass ]:
481.17400

[ PSA ]:
156.38000

[ LogP ]:
2.01500

[ Index of Refraction ]:
1.685

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QI9293220
CHEMICAL NAME :
5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hex opyranosyl)oxy)- 7,8,9,10-tetrahydro-6,8-dihydroxy-, (8S-cis)-
CAS REGISTRY NUMBER :
84082-03-1
LAST UPDATED :
198806
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C26-H27-N-O8
MOLECULAR WEIGHT :
481.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
1 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,5499,1986

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (2S)-2-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,2-oxazol-3-yl]formamido}-3-hydroxypropanoic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3-bromo-4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]benzoic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-4-methylpentanoic acid
  • tert-butyl (2R)-2-amino-3-methanesulfonylpropanoate hydrochloride