N-Boc-4-oxo-L-proline

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Names

[ CAS No. ]:
84348-37-8

[ Name ]:
N-Boc-4-oxo-L-proline

[Synonym ]:
MFCD01860669
1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-4-oxo-L-proline
N-Boc-4-oxo-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)-
(S)-1-Boc-4-oxo-2-pyrrolidinecarboxylic acid
T5N CVTJ AVOX1&1&1 EVQ &&S or L Form
N-t-boc-4-oxo-L-proline
(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-oxopyrrolidine-2-carboxylic acid
Boc-4-oxo-Pro-OH

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
390.8±42.0 °C at 760 mmHg

[ Melting Point ]:
160 °C (dec.)

[ Molecular Formula ]:
C10H15NO5

[ Molecular Weight ]:
229.230

[ Flash Point ]:
190.1±27.9 °C

[ Exact Mass ]:
229.095016

[ PSA ]:
83.91000

[ LogP ]:
-0.44

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.516

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Boc-Hyp-OH
  • Sulfuric acid
  • Oxalyl chloride
  • (trans)-1-[(1,1-dimethylethoxy)carbonyl]-4-hydroxy-L-proline
  • Di-tert-butyl dicarbonate
  • L-Hydroxyproline
  • N-BOC-cis-4-Hydroxy-L-proline

DownStream

  • L-Hydroxyproline
  • N-t-BOC-4-Methylene-L-proline
  • N-BOC-cis-4-Hydroxy-L-proline
  • (2S)-N2-(2,1,3-benzothiadiazol-4-yl)-N1-(3,5-dichlorophenyl)-4-oxo-1,2-pyrrolidinedicarboxamide
  • 2,1,3-Benzothiadiazol-4-amine
  • Boc-4-oxo-Pro-OMe
  • N-Boc-trans-4-amino-L-proline methyl ester
  • Boc-Hyp-OH
  • ditert-butyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate
  • (2S-trans)-4-Azido-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-Boc-4-oxo-L-proline methyl ester
  • N-Boc-4-oxo-L-proline methyl ester
  • N-Boc-4-oxo-L-proline tert-butyl ester
  • (r)-n-boc-4-oxo-l-proline tert-butyl ester
  • 4-FLUOROBENZOYLACETONITRILE N-BOC-4-OXO-L-PROLINE
  • N-Boc-4-Oxo-D-proline