3'-amino-2',3'-dideoxyuridine

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Names

[ CAS No. ]:
84472-86-6

[ Name ]:
3'-amino-2',3'-dideoxyuridine

[Synonym ]:
Uridine,3'-amino-2',3'-dideoxy
3'-Amino-2',3'-dideoxyuridine
3'-NH2-ddU
AMddU

Chemical & Physical Properties

[ Density]:
1.425

[ Melting Point ]:
174-176ºC

[ Molecular Formula ]:
C9H13N3O4

[ Molecular Weight ]:
227.21700

[ Exact Mass ]:
227.09100

[ PSA ]:
110.34000

[ Index of Refraction ]:
1.58

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • navuridine
  • Uridine,3'-azido-2',3'-dideoxy-5'-O-(triphenylmethyl)- (9CI)
  • 1-[4-methylsulfonyloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 5'-Trt-2'-dU
  • 1-[4-methylsulfonyloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 1-[4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • 2,3'-anhydro-1-(2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)uracil

DownStream

  • 1-[(2R,4S,5S)-5-(hydroxymethyl)-4-(2-methyl-4-nitroimidazol-1-yl)oxolan-2-yl]pyrimidine-2,4-dione

Related Compounds

  • 3'--Amino-2',3'-dideoxyuridine
  • 3’-β-Amino-2’,3’-dideoxy-5’-O-methoxy trityluridine
  • 3'-amino-2',3'-dideoxy-5-methoxymethyluridine
  • 3’-β-Amino-2’,3’-dideoxy-5’-O-trityl-5-methyl uridine
  • 3'-Amino-2',3'-dideoxy-5-methylcytidine
  • 3'-Amino-2',3'-dideoxy-5-chlorouridine