6-Chloro-5-nitropyridin-2-amine

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Names

[ CAS No. ]:
84487-03-6

[ Name ]:
6-Chloro-5-nitropyridin-2-amine

[Synonym ]:
6-chloro-5-nitropyridin-2-amine

Chemical & Physical Properties

[ Density]:
1.596g/cm3

[ Boiling Point ]:
393.6ºC at 760 mmHg

[ Molecular Formula ]:
C5H4ClN3O2

[ Molecular Weight ]:
173.55700

[ Flash Point ]:
191.9ºC

[ Exact Mass ]:
172.99900

[ PSA ]:
84.73000

[ LogP ]:
2.32980

[ Index of Refraction ]:
1.657

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US1813370
CHEMICAL NAME :
Pyridine, 2-amino-6-chloro-5-nitro-
CAS REGISTRY NUMBER :
84487-03-6
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H4-Cl-N3-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1783 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1427 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
512 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
392 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloro-3-nitropyridine

DownStream

  • 2-Pyridinamine,6-(ethylthio)-5-nitro-(9CI)

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 6-CHLORO-5-NITROPYRIDIN-2(1H)-ONE
  • 6-Chloro-5-iodo-3-nitropyridin-2-amine
  • 6-Chloro-5-methyl-3-nitro-2-pyridinamine
  • 3-Chloro-5-nitropyridin-2-amine
  • methyl 4-(2-(6-chloro-5-nitropyridin-2-yl)ethyl)benzoate
  • N-(2-CHLORO-3-NITRO-6-PYRIDYL)ACETAMIDE
  • 2-(1-ethyl-1H-pyrazol-5-yl)-1-(propan-2-yl)pyrrolidin-3-amine
  • 3-Amino-3-(3-nitrophenyl)butan-1-ol
  • 2-(1-Amino-2-methyl-2-phenylcyclopropyl)ethan-1-ol
  • 2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-6-yl}ethan-1-ol
  • 2-{hexahydro-2H-furo[3,2-b]pyrrol-5-yl}ethan-1-ol
  • 5-(2-Hydroxyethyl)-1-methylpiperazin-2-one
  • 5-cyclobutyl-1-(pyridin-4-yl)-1H-pyrazole-3-carboxylic acid
  • 5-cyclopropyl-1-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid
  • 1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methoxycarbonyl)cyclohexane-1-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methylbutanoic acid
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