methyl 4-[[4-[(5-chloro-2-oxoindol-3-yl)amino]benzoyl]amino]benzoate

Names

[ CAS No. ]:
84496-05-9

[ Name ]:
methyl 4-[[4-[(5-chloro-2-oxoindol-3-yl)amino]benzoyl]amino]benzoate

Chemical & Physical Properties

[ Density]:
1.4g/cm3

[ Molecular Formula ]:
C23H16ClN3O4

[ Molecular Weight ]:
433.84400

[ Exact Mass ]:
433.08300

[ PSA ]:
100.35000

[ LogP ]:
4.97380

[ Index of Refraction ]:
1.672

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG4995760
CHEMICAL NAME :
Benzoic acid, 4-((4-((5-chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene )amino)benzoyl)amino) -, methyl ester
CAS REGISTRY NUMBER :
84496-05-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H16-Cl-N3-O4
MOLECULAR WEIGHT :
433.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 21,775,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Chloroindoline-2,3-dione
  • methyl 4-[(4-nitrobenzoyl)amino]benzoate
  • 4-Nitrobenzoyl chloride
  • Methyl 4-aminobenzoate

DownStream

  • methyl 4-[[4-[[5-chloro-2-oxo-1-(piperidin-1-ylmethyl)indol-3-ylidene]amino]benzoyl]amino]benzoate

Related Compounds

  • 5-(4-methoxyphenyl)-N-(pyridin-4-yl)oxazole-2-carboxamide
  • N-(benzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)oxazole-2-carboxamide
  • N-(2-chlorophenyl)-5-(4-methoxyphenyl)oxazole-2-carboxamide
  • N-(2-ethylphenyl)-5-(4-methoxyphenyl)oxazole-2-carboxamide
  • N-(2-chlorobenzyl)-5-(4-methoxyphenyl)oxazole-2-carboxamide
  • 4-Vinyl-1-naphthol
  • (2E)-2-[(oxan-2-yl)methylidene]butanoic acid
  • 2-Chloro-4-fluoro-3-methyl-5-nitrobenzoyl chloride
  • 3-(2,4-Dichloro-benzyl)-1-(4-oxo-cyclohexyl)-pyrrolidin-2-one
  • (3-Amino-1-benzothien-2-YL)(phenyl)methanone
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