4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER

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Names

[ CAS No. ]:
84501-68-8

[ Name ]:
4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER

[Synonym ]:
norastemizole ethyl carbamate
EINECS 282-988-5
N-Ethoxycarbonyl Norastemizole

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
573.5ºC at 760mmHg

[ Molecular Formula ]:
C22H25FN4O2

[ Molecular Weight ]:
396.45800

[ Flash Point ]:
300.6ºC

[ Exact Mass ]:
396.19600

[ PSA ]:
59.39000

[ LogP ]:
4.26740

[ Index of Refraction ]:
1.627

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate
  • 4-Fluorobenzyl chloride
  • N-Carbethoxy-4-amino-piperidone
  • 1-(4-Fluorobenzyl)-2-chloro-benzimidazole
  • Chloroform
  • ethyl 4-isocyanopiperidine-1-carboxylate
  • 1-N-[(4-fluorophenyl)methyl]benzene-1,2-diamine
  • ethyl 4-isothiocyanatopiperidine-1-carboxylate
  • ethyl 4-{[(2-aminophenyl)aminothioxomethyl]amino}-1-piperidinecarboxylate
  • 2-Hydroxybenzimidazole

DownStream

  • Astemizole
  • O-Desmethyl Astemizole
  • 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
  • Norastemizole Hydrobromide
  • norastemizole

Related Compounds

  • 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]carbonyl]-1-piperidinecarboxylic acid,1,1-dimethylethyl ester
  • 2,2,2-Trifluoro-1-(4-methylcyclohexyl)ethan-1-amine
  • ((4-Methylcyclohexyl)methyl)hydrazine
  • Cyclohexanecarboxylic acid, 1-[[(2-methoxyethyl)methylamino]methyl]-4-methyl-
  • 2-(4-Methylcyclohexyl)cyclopropane-1-carboxylic acid
  • Methyl 2-hydroxy-2-(4-methylcyclohexyl)acetate
  • 1-(3-Phenylbutyl)-4-piperidinone
  • Propyl({[4-(trifluoromethyl)cyclohexyl]methyl})amine
  • (Propan-2-yl)({[4-(trifluoromethyl)cyclohexyl]methyl})amine
  • N-{[4-(trifluoromethyl)cyclohexyl]methyl}cyclopropanamine
  • 3-Amino-3-cycloheptylpropan-1-ol
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