4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER

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Names

[ CAS No. ]:
84501-68-8

[ Name ]:
4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER

[Synonym ]:
norastemizole ethyl carbamate
EINECS 282-988-5
N-Ethoxycarbonyl Norastemizole

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
573.5ºC at 760mmHg

[ Molecular Formula ]:
C22H25FN4O2

[ Molecular Weight ]:
396.45800

[ Flash Point ]:
300.6ºC

[ Exact Mass ]:
396.19600

[ PSA ]:
59.39000

[ LogP ]:
4.26740

[ Index of Refraction ]:
1.627

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate
  • 4-Fluorobenzyl chloride
  • N-Carbethoxy-4-amino-piperidone
  • 1-(4-Fluorobenzyl)-2-chloro-benzimidazole
  • Chloroform
  • ethyl 4-isocyanopiperidine-1-carboxylate
  • 1-N-[(4-fluorophenyl)methyl]benzene-1,2-diamine
  • ethyl 4-isothiocyanatopiperidine-1-carboxylate
  • ethyl 4-{[(2-aminophenyl)aminothioxomethyl]amino}-1-piperidinecarboxylate
  • 2-Hydroxybenzimidazole

DownStream

  • Astemizole
  • O-Desmethyl Astemizole
  • 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
  • Norastemizole Hydrobromide
  • norastemizole

Related Compounds

  • 3-(1-Hydroxy-1-methylethyl)-4-methyl-2(1H)-pyridinone
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylpropanoyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 5-(2-Hydroxypropan-2-yl)pyrimidin-4(3H)-one
  • 3-Amino-1-(2-bromopyridin-3-yl)propan-1-one
  • (2R)-2-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylpentanamido}pentanoic acid
  • 4-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylpentanoyl}morpholine-3-carboxylic acid
  • 1-(6-Fluoro-1-benzofuran-2-yl)butan-1-one
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
  • rac-(1R,3S)-3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,2,5-oxadiazole-3-amido]cyclohexane-1-carboxylic acid
  • 5-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-1-methyl-1H-pyrazole-4-carboxylic acid
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