(2s, 4r)-boc-gamma-mso-proline methyl ester

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Names

[ CAS No. ]:
84520-67-2

[ Name ]:
(2s, 4r)-boc-gamma-mso-proline methyl ester

[Synonym ]:
1-O-tert-butyl 2-O-methyl (2S,4R)-4-methylsulfonyloxypyrrolidine-1,2-dicarboxylate
1,2-Pyrrolidinedicarboxylic acid, 4-[(methylsulfonyl)oxy]-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
2-Methyl 1-(2-methyl-2-propanyl) (2S,4R)-4-[(methylsulfonyl)oxy]-1,2-pyrrolidinedicarboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
443.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H21NO7S

[ Molecular Weight ]:
323.363

[ Flash Point ]:
222.1±28.7 °C

[ Exact Mass ]:
323.103882

[ PSA ]:
107.59000

[ LogP ]:
-0.10

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.505

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Boc-trans-D-Hyp-OMe
  • Methanesulfonyl chloride
  • Boc-Hyp-OMe
  • (2S)-methyl 1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
  • (trans)-1-[(1,1-dimethylethoxy)carbonyl]-4-hydroxy-L-proline
  • 1-Tert-butyl2-Methyl4-hydroxypyrrolidine-1,2-dicarboxylate
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • SodiuM bicarbonate
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE

DownStream

  • n-boc-cis-4-cyano-l-proline methyl ester
  • (2S,4R)-1-(TERT-BUTOXYCARBONYL)-4-((METHYLSULFONYL)OXY)PYRROLIDINE-2-CARBOXYLIC ACID
  • methyl n-boc-l-proline-3-ene
  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester
  • (2S,4S)-1-(tert-butoxycarbonyl)-4-cyanopyrrolidine-2-carboxylic acid
  • (2S,4S)-1-(tert-Butoxycarbonyl)-4-azidopyrrolidine-2-carboxylic acid
  • (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
  • N-Boc-trans-4-amino-L-proline methyl ester
  • Boc-trans-4-cyano-L-proline methyl ester
  • (2S-trans)-4-Azido-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester

Related Compounds

  • (2S,4R)-METHYL 1-BENZOYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
  • (2S,4R)-1-Benzyl 2-methyl 4-((tert-butoxycarbonyl)amino)pyrrolidine-1,2-dicarboxylate
  • (2S,4R)-4-hydroxy-2-methoxycarbonyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
  • (2S,4R)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE-2-CARBOXYLATE
  • (2S,4R)-1-BENZYL-2-METHYL-4-FLUOROPYRROLIDINE-1,2-DICARBOXYLATE