ICI 162,846

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Names

[ CAS No. ]:
84545-30-2

[ Name ]:
ICI 162,846

[Synonym ]:
Tocris-0833

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
500.4ºC at 760 mmHg

[ Molecular Formula ]:
C11H17F3N6O

[ Molecular Weight ]:
306.29

[ Flash Point ]:
256.5ºC

[ Exact Mass ]:
306.14200

[ PSA ]:
108.82000

[ LogP ]:
2.30120

[ Index of Refraction ]:
1.563

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ7889000
CHEMICAL NAME :
1H-Pyrazole-1-pentanamide, 3-((imino((2,2,2-trifluoroethyl)amino)methyl)amino)-
CAS REGISTRY NUMBER :
84545-30-2
LAST UPDATED :
199507
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H17-F3-N6-O
MOLECULAR WEIGHT :
306.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
365 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 15,366,1987

Related Compounds

  • ICI 89406
  • 2-(3,4-dichlorophenyl)-N-[1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-ylethyl]-N-methylacetamide,hydrochloride
  • ICI 69322
  • 2-(3,4-dichlorophenyl)-N-methyl-N-[(2S)-3-methyl-1-pyrrolidin-1-ylbutan-2-yl]acetamide,hydrochloride
  • ICI 192605
  • ici 174,864
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-Pyridinecarbonitrile, 1-butyl-1,2,5,6-tetrahydro-4-methyl-2,6-dioxo-5-[[[4-(2-phenyldiazenyl)phenyl]amino]methylene]-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • trans-2-[(3,4-Dimethylphenyl)amino]cyclobutan-1-ol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine