Bitopertin

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Names

[ CAS No. ]:
845614-11-1

[ Name ]:
Bitopertin

[Synonym ]:
[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone
RG 1678
Paliflutine
Paliflutine [INN]
(S)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-(2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone
Bitopertin

Chemical & Physical Properties

[ Molecular Formula ]:
C21H20F7N3O4S

[ Molecular Weight ]:
543.45500

[ Exact Mass ]:
543.10600

[ PSA ]:
88.19000

[ LogP ]:
5.01870

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-Fluoro-5-(trifluoromethyl)pyridin-2-yl)piperazine
  • (S)-2-(1-Methyl-2,2,2-trifluoroethoxy)-5-Methylsulfonylbenzoic acid

DownStream

Related Compounds

  • Bitopertin (R enantiomer)
  • Sodium 7-methyl-2-naphthalenesulfonate
  • Ethyl 5-(2-chloropropanamido)pyrazolo[1,5-a]pyridine-3-carboxylate
  • 1-Chloro-4-methoxynaphthalen-2-ol
  • CID 91666527
  • (2S)-4-methyl-2-[(2,2,2-trifluoroethyl)amino]pentanoic acid
  • (E)-3-(furan-2-yl)-1-(4-(quinoxalin-2-yloxy)piperidin-1-yl)prop-2-en-1-one
  • 2-methyl-6-(4-(quinoxalin-2-yloxy)piperidine-1-carbonyl)pyridazin-3(2H)-one
  • 1-(4-Chlorophenyl)-4-(4-(quinoxalin-2-yloxy)piperidin-1-yl)butane-1,4-dione
  • 3-(2-oxo-2-(4-(quinoxalin-2-yloxy)piperidin-1-yl)ethyl)quinazolin-4(3H)-one
  • (5-Bromopyridin-3-yl)(4-(quinoxalin-2-yloxy)piperidin-1-yl)methanone