Enalaprilat Dihydrate

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Names

[ Name ]:
Enalaprilat Dihydrate

[Synonym ]:
MFCD00941393
ENALAPRILAT DIHYDRATE
2-[N-(1-Carboxy-3-phenylpropyl)alanyl]-1-pyrrolidinecarboxylic acid dihydrate
EINECS 278-459-3
1-Pyrrolidinecarboxylic acid, 2-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxopropyl]-, hydrate (1:2)

Chemical & Physical Properties

[ Boiling Point ]:
563.5ºC at 760 mmHg

[ Melting Point ]:
211-215°C

[ Molecular Formula ]:
C₁₈H₂₈N₂O₇

[ Molecular Weight ]:
384.424

[ Flash Point ]:
294.6ºC

[ Exact Mass ]:
384.189636

[ PSA ]:
125.40000

[ LogP ]:
1.32630

[ Index of Refraction ]:
1.579

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S22-S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
TW3590600

Articles

Evaluation of a rapid method for the therapeutic drug monitoring of aliskiren, enalapril and its active metabolite in plasma and urine by UHPLC-MS/MS.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 980 , 79-87, (2015)

Given the increasing popularity of aliskiren, particularly in combination with angiotensin converting enzyme inhibitor (e.g. enalapril), it is important to determine whether its use in combination wit...

Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat.

Drug Metab. Dispos. 42(9) , 1567-74, (2014)

Hepatic uptake and efflux transporters govern the systemic and hepatic exposure of many drugs and metabolites. Enalapril is a pharmacologically inactive prodrug of enalaprilat. Following oral administ...

Enalaprilat.

Dimens. Crit. Care Nurs. 19(2) , 22, (2000)

Enalaprilat D5
Enalaprilat-d5 Sodium Salt
Enalaprilat
(2S)-1-[(2S)-2-[[(2S)-1-oxo-4-phenyl-1-phenylmethoxybutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-butoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
Enalaprilat tert-Butyl Ester
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
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Methyl 2-(5-bromo-2-(2-((tert-butoxycarbonyl)amino)acetyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate
1,1-Difluoro-2-methylpropan-2-amine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
Methyl 3-methyl-tetradecanoate
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde