2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-(difluoromethylthio)phenyl)-1,4-dihydropyridine

Suppliers

Names

[ CAS No. ]:
84761-73-9

[ Name ]:
2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-(difluoromethylthio)phenyl)-1,4-dihydropyridine

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
462ºC at 760 mmHg

[ Molecular Formula ]:
C20H23F2NO4S

[ Molecular Weight ]:
411.46300

[ Flash Point ]:
233.2ºC

[ Exact Mass ]:
411.13200

[ PSA ]:
89.93000

[ LogP ]:
4.69110

[ Index of Refraction ]:
1.553

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7969900
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(o-(difluoromethylthio)phenyl)-2,6-dime thyl-, diethyl ester
CAS REGISTRY NUMBER :
84761-73-9
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H23-F2-N-O4-S
MOLECULAR WEIGHT :
411.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Vascular - regional or general arteriolar or venous dilation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,817,1982

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine