Norgestrienone
Suppliers
Names
Chemical & Physical Properties
[ Density]:
1.21g/cm3
[ Boiling Point ]:
498.1ºC at 760 mmHg
[ Melting Point ]:
169ºC
[ Molecular Formula ]:
C20H22O2
[ Molecular Weight ]:
294.38700
[ Flash Point ]:
211.2ºC
[ Exact Mass ]:
294.16200
[ PSA ]:
37.30000
[ LogP ]:
3.33270
[ Index of Refraction ]:
1.615
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8960080
- CHEMICAL NAME :
- 19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
- CAS REGISTRY NUMBER :
- 848-21-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H22-O2
- MOLECULAR WEIGHT :
- 294.42
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1168 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1642 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 1 mg/kg
- SEX/DURATION :
- female 36 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979