Norgestrienone

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Names

[ CAS No. ]:
848-21-5

[ Name ]:
Norgestrienone

[Synonym ]:
Ethynyl trienolone
Ogyline

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
498.1ºC at 760 mmHg

[ Melting Point ]:
169ºC

[ Molecular Formula ]:
C20H22O2

[ Molecular Weight ]:
294.38700

[ Flash Point ]:
211.2ºC

[ Exact Mass ]:
294.16200

[ PSA ]:
37.30000

[ LogP ]:
3.33270

[ Index of Refraction ]:
1.615

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8960080
CHEMICAL NAME :
19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
CAS REGISTRY NUMBER :
848-21-5
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H22-O2
MOLECULAR WEIGHT :
294.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1168 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1642 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
1 mg/kg
SEX/DURATION :
female 36 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979

Related Compounds

  • Norgestrienone
  • [3-(2-Fluoro-6-methoxy-4-methylphenyl)-2,2-dimethylcyclopropyl]methanamine
  • 1-[1-(3-Cyclopropylphenyl)cyclopropyl]ethan-1-amine
  • 1'-[(tert-butoxy)carbonyl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,4-dihydrospiro[1-benzopyran-2,3'-pyrrolidine]-6-carboxylic acid
  • (1R)-1-[4-chloro-2-(trifluoromethyl)phenyl]-2,2,2-trifluoroethan-1-ol
  • (2S)-4-[3-(trifluoromethyl)-1H-pyrazol-4-yl]butan-2-amine
  • 1-[3-(Methoxymethyl)furan-2-yl]-2,2-dimethylcyclopropane-1-carboxylic acid
  • rac-(1R,3S)-3-(4-methoxypyridin-2-yl)-2,2-dimethylcyclopropan-1-amine
  • 1-(2-Fluoro-5-nitrophenyl)-2-methylpropan-2-amine
  • 3-(3-Cyclopropylphenyl)-3,3-difluoropropanoic acid
  • rac-(1R,2R)-2-[5-(trifluoromethyl)thiophen-2-yl]cyclopropan-1-amine
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