4-Morpholinecarboxamide, N-(4-fluorophenyl)-

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Names

[ CAS No. ]:
84882-84-8

[ Name ]:
4-Morpholinecarboxamide, N-(4-fluorophenyl)-

[Synonym ]:
4-Morpholinecarboxamide,N-(4-fluorophenyl)
N-(4-Fluorophenyl)-4-morpholinecarboxamide
Morpholine-4-carboxylic acid (4-fluoro-phenyl)-amide

Chemical & Physical Properties

[ Density]:
1.308g/cm3

[ Boiling Point ]:
419.4ºC at 760 mmHg

[ Molecular Formula ]:
C11H13FN2O2

[ Molecular Weight ]:
224.23200

[ Flash Point ]:
207.4ºC

[ Exact Mass ]:
224.09600

[ PSA ]:
41.57000

[ LogP ]:
1.70070

[ Index of Refraction ]:
1.584

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD9804000
CHEMICAL NAME :
4-Morpholinecarboxamide, N-(4-fluorophenyl)-
CAS REGISTRY NUMBER :
84882-84-8
LAST UPDATED :
199204
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H13-F-N2-O2
MOLECULAR WEIGHT :
224.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,339,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,339,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(Chloroformyl)morpholine
  • 4-Fluoroaniline

DownStream

Related Compounds

  • 4-Morpholinecarboxamide,N-[4-(aminocarbonyl)phenyl]-(9CI)
  • 4-Morpholinecarboxamide,N-[4-(dimethylamino)phenyl]-(9CI)
  • 4-[N-(4-fluorophenyl)-C-methylcarbonimidoyl]-5-phenylfuran-2,3-dione
  • 4-[N-(4-fluorophenyl)-C-methylcarbonimidoyl]-5-methylfuran-2,3-dione
  • (4-(N-(4-Fluorophenyl)sulfamoyl)phenyl)boronic acid
  • 4-(N-(4-fluorophenyl)-4-formylanilino)benzaldehyde
  • 4-cyclopropyl-1-methyl-3-{1-[2-oxo-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one
  • 6-[4-(4-cyclopropyl-1-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)piperidin-1-yl]pyridine-3-carbonitrile
  • 4-{[5-(Oxan-4-yl)-1,2,4-oxadiazol-3-yl]methyl}-2-(piperidine-1-carbonyl)morpholine
  • 2-[(Azetidin-3-yl)methyl]-6-fluorophenol
  • 2-Amino-2-(1-phenylcyclopentyl)ethan-1-ol
  • Fmoc-Sec(Mob)-OPfp
  • (4-Methoxy-3,5-dimethylphenyl)methyl sulfamate
  • 1-[4-(Bromomethyl)-2-fluorophenyl]piperidin-2-one
  • 4-(Nitromethyl)benzene-1,2-diol
  • 4-(3,5-Dichloropyridin-2-yl)-2-(thiomorpholine-4-carbonyl)morpholine
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