1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid

Suppliers

Names

[ Name ]:
1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid

[Synonym ]:
1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic acid
1-[(4-fluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid
Cyclopropanecarboxylic acid, 1-[[(4-fluorophenyl)amino]carbonyl]-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
475.2±30.0 °C at 760 mmHg

[ Melting Point ]:
175 °C

[ Molecular Formula ]:
C₁₁H₁₀FNO₃

[ Molecular Weight ]:
223.200

[ Flash Point ]:
241.2±24.6 °C

[ Exact Mass ]:
223.064468

[ PSA ]:
66.40000

[ LogP ]:
0.95

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.651

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Cyclopropane-1,1-dicarboxylic acid
4-Fluoroaniline
METHYL 1-[(4-FLUOROPHENYL)CARBAMOYL]CYCLOPROPANECARBOXYLATE
1-(Methoxycarbonyl)cyclopropanecarboxylic acid
Diethyl 1,1-cyclopropanedicarboxylate

DownStream

Foretinib (GSK1363089)
Cabozantinib (XL184, BMS-907351)
Cabozantinib malate (XL184)
N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

2-(3-Bromo-6-chloropyridin-2-yl)malononitrile
(3-Methyloxolan-3-yl)methanethiol
{5-Oxa-2-azaspiro[3.5]nonan-6-yl}methanol
3-(3-Bromophenyl)spiro[3.3]heptan-1-one
Ethyl 9-hydroxy-5-methylbicyclo[3.3.1]nonane-1-carboxylate
1-{2-Methylpyrido[3,4-d]pyrimidin-4-yl}-4-(2,2,2-trifluoroethyl)piperazine
4-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]piperazin-2-one
1-Chloro-5-fluoro-2-isocyanato-4-methylbenzene
1-Tert-butyl-3-[(11-sulfanylundecyl)oxy]urea
1-Hydroxy-2-(trifluoromethyl)cyclopropane-1-carboxylic acid