1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid

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Names

[ CAS No. ]:
849217-48-7

[ Name ]:
1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid

[Synonym ]:
1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic acid
1-[(4-fluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid
Cyclopropanecarboxylic acid, 1-[[(4-fluorophenyl)amino]carbonyl]-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
475.2±30.0 °C at 760 mmHg

[ Melting Point ]:
175 °C

[ Molecular Formula ]:
C11H10FNO3

[ Molecular Weight ]:
223.200

[ Flash Point ]:
241.2±24.6 °C

[ Exact Mass ]:
223.064468

[ PSA ]:
66.40000

[ LogP ]:
0.95

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.651

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyclopropane-1,1-dicarboxylic acid
  • 4-Fluoroaniline
  • METHYL 1-[(4-FLUOROPHENYL)CARBAMOYL]CYCLOPROPANECARBOXYLATE
  • 1-(Methoxycarbonyl)cyclopropanecarboxylic acid
  • Diethyl 1,1-cyclopropanedicarboxylate

DownStream

  • Foretinib (GSK1363089)
  • Cabozantinib (XL184, BMS-907351)
  • Cabozantinib malate (XL184)
  • N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 3-Methylethcathinone hydrochloride
  • 3-Fluoroethcathinone hydrochloride
  • 2-(Ethylamino)-1-(o-tolyl)propan-1-one,monohydrochloride
  • 2-(Dimethylamino)-1-(p-tolyl)butan-1-one,monohydrochloride
  • 2-(Methylamino)-1-(m-tolyl)butan-1-one,monohydrochloride
  • 2,4-Dimethylmethcathinone hydrochloride
  • N-(2-hydroxyethyl)-octadecanamide-18,18,18-d3
  • 1-[(4-Bromo-2,5-dimethoxyphenyl)methyl]-piperazine,dihydrochloride
  • Mepirapim hydrochloride
  • Mescaline-NB2OMe.HCl
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