6-Thioguanosine

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Names

[ CAS No. ]:
85-31-4

[ Name ]:
6-Thioguanosine

[Synonym ]:
2-amino-6-mercaptopurine ribose
thioguanosine
sri759
EINECS 201-597-2
6-MERCAPTOGUANOSINE
6-thio-guanosine
6-thioguanineribose
ribosylthioguanine
6-thio-guanosin
2-AMINO-6-MERCAPTOPURINE-9-D-RIBOSIDE HYDRATE
MFCD00005736
thioguanineriboside
TGR

Chemical & Physical Properties

[ Density]:
2.18 g/cm3

[ Boiling Point ]:
756.9ºC at 760 mmHg

[ Melting Point ]:
230-231°C

[ Molecular Formula ]:
C10H13N5O4S

[ Molecular Weight ]:
299.31

[ Flash Point ]:
411.6ºC

[ Exact Mass ]:
299.06900

[ PSA ]:
174.53000

[ Storage condition ]:
-20°C Freezer

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UP0200000
CHEMICAL NAME :
9H-Purine-6-thiol, 2-amino-9-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER :
85-31-4
LAST UPDATED :
199410
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H13-N5-O4-S
MOLECULAR WEIGHT :
299.34
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ GZ ISH D- BT5OTJ CQ DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 3,181,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
156 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

Safety Information

[ Risk Phrases ]:
24/25

[ RTECS ]:
UP0200000

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

DownStream

  • 2-amino-9-(β-D-ribofuranosyl)purine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 6-Thioguanosine hydrate
  • 5'-deoxy-6-thioguanosine
  • 7-Methyl-6-thioguanosine
  • 1-METHYL-6-THIOGUANOSINE
  • 2'-Deoxy-6-thioguanosine
  • 6-Thioguanosine-5'-phosphate