2-Benzoylbenzoic acid

Suppliers

Names

[ CAS No. ]:
85-52-9

[ Name ]:
2-Benzoylbenzoic acid

[Synonym ]:
ortho-benzoyl benzoic acid
o-Benzoyl Benzoic Acid
2-benzoyl benzoic acid
benzoylbenzoic acid
o-benzoyl-benzoicaci
carboxybenzophenone
RARECHEM AL BO 1426
1-carboxy-2-phenylcarbonylbenzene
MFCD00002472
OBBA
EINECS 201-612-2
Benzoic acid, 2-benzoyl-
O-BENZOYLBENZOIC ACID
2-CARBOXYBENZOPHENONE
2-benzoyl-benzoicaci
2-Benzoylbenzoic acid
skp10a

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
436.4±28.0 °C at 760 mmHg

[ Melting Point ]:
126-129 °C(lit.)

[ Molecular Formula ]:
C₁₄H₁₀O₃

[ Molecular Weight ]:
226.227

[ Flash Point ]:
231.9±20.5 °C

[ Exact Mass ]:
226.062988

[ PSA ]:
54.37000

[ LogP ]:
2.31

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.617

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG3600000

CHEMICAL NAME :: Benzoic acid, o-benzoyl-

CAS REGISTRY NUMBER :: 85-52-9

BEILSTEIN REFERENCE NO. :: 1107841

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H10-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4600 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(11),52,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 880 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(11),52,1971

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DG3600000

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Phthalic anhydride
benzene
2-Bromobenzoic acid
Lithium o-Lithiobenzoate
Benzoyl chloride
2-benzoylbenzonitrile
benzoic acid
N-methoxybenzamide
o-methylbenzophenone

DownStream

(S)-(-)-Limonene
Methyl 2-benzoylbenzoate
3-Methoxy-3-phenyl-2-benzofuran-1(3H)-one
2-benzoylbenzonitrile
(+)-Limonene
1(3H)-Isobenzofuranone,3-(1-methylethoxy)-3-phenyl-
3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-benzofuran-1-one
5H-Dibenz[b,e]azepine,6,11-dihydro-
2-(1-PHENYL-2,3-DIHYDRO-1H-ISOINDOL-2-YL)ETHANOL
7-phenyl-9-oxa-8-azabicyclo[4.4.0]deca-1,3,5,7-tetraen-10-one

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Photosensitizing properties of compounds related to benzophenone.

Acta Derm. Venereol. 93(1) , 30-2, (2013)

Benzophenone is a phototoxic compound with absorption maxima in the ultraviolet A (UVA) and ultraviolet B (UVB) range. Many benzophenone derivatives are known to be photosensitizing. On the other hand...

Mass spectrometric behavior of phenolic acids standards and their analysis in the plant samples with LC/ESI/MS system.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 21-7, (2014)

Liquid chromatography coupled to mass spectrometry (MS) with electrospray ionization (ESI) is one of analytical techniques to obtain accurate results of low molecular weight aromatic compounds in biol...

Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.

Bioorg. Med. Chem. Lett. 15 , 5170-5, (2005)

Nonsteroidal anti-inflammatory drugs (NSAIDs) like indomethacin, flufenamic acid, and related compounds have been recently identified as potent inhibitors of AKR1C3. We report that some other NSAIDs (...