TCO-OH

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Names

[ CAS No. ]:
85081-69-2

[ Name ]:
TCO-OH

[Synonym ]:
(E)-CYCLOOCT-4-ENOL
4-Cycloocten-1-ol, (E)-
(E)-Cyclooct-4-enol

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₄O

[ Molecular Weight ]:
126.19600

[ Exact Mass ]:
126.10400

[ PSA ]:
20.23000

[ LogP ]:
1.86760

[ Storage condition ]:
20°C

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Hazard Codes ]:
C

[ Risk Phrases ]:
41-52

[ Safety Phrases ]:
26-39

[ RIDADR ]:
NONH for all modes of transport

Articles

Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation.

Bioconjug. Chem. 22 , 2263-2270, (2011)

1,2,4,5-Tetrazines have been established as effective dienes for inverse electron demand [4 + 2] Diels-Alder cycloaddition reactions with strained alkenes for over 50 years. Recently, this reaction pa...

Tetrazine-based cycloadditions: application to pretargeted live cell imaging.

Bioconjug. Chem. 19 , 2297-2299, (2008)

Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. T...

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity.

J. Am. Chem. Soc. 130 , 13518-13519, (2008)

Described is a bioorthogonal reaction that proceeds with unusually fast reaction rates without need for catalysis: the cycloaddition of s-tetrazine and trans-cyclooctene derivatives. The reactions tol...

(R)-TCO-OH
TCO-NHS ester
TCO-PEG8-NHS ester
TCO-PEG8-amine
TCO-PEG8-acid
TCO-pnb ester
N-cyclopropyl-2-(4-oxoquinazolin-3(4H)-yl)benzamide
(3-amino-4-methyl-1H-pyrazol-1-yl)acetonitrile
2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N-(3-methoxyphenyl)acetamide
(4-(3-methoxyphenyl)piperazin-1-yl)(1-methyl-1H-indol-5-yl)methanone
2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N-(6-methylpyridin-2-yl)acetamide
1-(4-methoxyphenyl)-4-[4-methyl-3-(1H-tetrazol-1-yl)benzoyl]piperazine
N-(3,4-dimethylphenyl)-7-methyl-4-oxo-1-(2-oxo-2-(propylamino)ethyl)-1,4-dihydro-1,8-naphthyridine-3-carboxamide
2-Ethylthiazol-5-amine
N-(3,5-dimethylphenyl)-7-methyl-4-oxo-1-[(phenylcarbamoyl)methyl]-1,4-dihydro-1,8-naphthyridine-3-carboxamide
3-chloro-N-(1-(furan-2-yl)propan-2-yl)-2-methylbenzenesulfonamide

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