3,4-Difluorobenzyl bromide

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Names

[ CAS No. ]:
85118-01-0

[ Name ]:
3,4-Difluorobenzyl bromide

[Synonym ]:
3, 4-DIFLUOROBENZYL BROMIDE
3,4-Difluorobenzylbromide
alpha-Bromo-3,4-difluorotoluene
3,4-Difluoro Bromine Benzyl
3 4-DIFLUOROBENZYL BROMIDE
4-(BROMOMETHYL)-1,2-DIFLUORO-BENZENE
3,4-DIFLUORBENZYLBROMID
Benzene, 4-(bromomethyl)-1,2-difluoro-
MFCD00009889
4-(Bromomethyl)-1,2-difluorobenzene
FR BF D1E
α-Bromo-3,4-difluorotoluene
ALPHA-BROMO-3,4-DIFLUOROTOLUEN
3,4-DIFLUORO-BROMOBENZYL
EINECS 285-653-1
3,4-Difluorobenzyl bromide

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
195.5±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H5BrF2

[ Molecular Weight ]:
207.015

[ Flash Point ]:
79.4±0.0 °C

[ Exact Mass ]:
205.954269

[ LogP ]:
2.93

[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.523

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S23-S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,4-Difluorotoluene

DownStream

  • 3,4-Difluorophenylalanine
  • 3,4-Difluorophenylalanine
  • BOC-L-3,4-Difluorophe

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Bioorg. Med. Chem. Lett. 22(8) , 2922-6, (2012)

A series of benzothiophene-based phosphonates was synthesized and many analogs within the series were shown to be potent antagonists of the TRPM8 channel. The compounds were obtained as a racemic mixt...


More Articles

Related Compounds

  • [(3,4-Difluorobenzyl)sulfanyl][(2E)-2-(2-thienylmethylene)hydrazino]methaniminium bromide
  • 3,4-Difluorobenzyl alcohol
  • 3,4-Difluorobenzyl chloride
  • 3-CHLORO-2,4-DIFLUOROBENZYL BROMIDE
  • 3-Ethoxy-2,4-difluorobenzyl bromide
  • 2,4-Difluorobenzyl bromide
  • Sodium 5-(methoxycarbonyl)-4-methylfuran-3-sulfinate
  • 2-{[2-(Aminomethyl)bicyclo[3.1.0]hexan-2-yl]oxy}ethan-1-ol
  • 4-amino-3-(1H-indazol-7-yl)butanoic acid
  • 6,8-Dibromo-4-chlorocoumarin
  • 4-Amino-1-[3-(4-Boc-1-piperazinyl)propyl]pyrazole
  • 2-Amino-2-(1-cycloheptylcyclopropyl)acetic acid
  • 4,6-Bis(benzyloxy)-3-methylbenzofuran
  • rac-(1R,2S)-2-cycloheptylcyclopropane-1-carboxylic acid
  • Ethyl 4-Chloro-5-methoxy-1-methyl-1H-indole-2-carboxylate
  • 2-(4-Bromophenyl)-1-(4-chlorophenyl)benzimidazole
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