1-Boc-3-hydroxypiperidine

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Names

[ CAS No. ]:
85275-45-2

[ Name ]:
1-Boc-3-hydroxypiperidine

[Synonym ]:
MFCD02093938
tert-butyl 3-hydroxypiperidine-1-carboxylate
2-Methyl-2-propanyl 3-hydroxy-1-piperidinecarboxylate
N-BOC-3-hydroxypiperidine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
292.3±33.0 °C at 760 mmHg

[ Melting Point ]:
65-67°C

[ Molecular Formula ]:
C10H19NO3

[ Molecular Weight ]:
201.263

[ Flash Point ]:
130.6±25.4 °C

[ Exact Mass ]:
201.136490

[ PSA ]:
49.77000

[ LogP ]:
0.49

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.496

[ Storage condition ]:
Store at -15°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Hydroxypiperidine
  • Di-tert-butyl dicarbonate
  • piperidin-3-ol hydrochloride
  • Di-tert-butyl carbonate
  • 2-Methyl-1,2-propanediamine

DownStream

  • tert-butyl 3-methoxypiperidine-1-carboxylate
  • N-BOC-2-Piperidinecarboxylic acid
  • 1-Boc-3-Piperidinone
  • 1-BOC-1,2,3,6-tetrahydropyridine
  • N-(3-Piperidinyl)acetamide
  • tert-butyl 3-azidopiperidine-1-carboxylate
  • (S)-1-BOC-2-(HYDROXYMETHYL)PIPERIDINE
  • tert-butyl 2-benzylpiperidine-1-carboxylate
  • (R)-1-Boc-3-Hydroxypiperidine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • S-1-Boc-3-hydroxypiperidine
  • R-1-Boc-3-hydroxypiperidine
  • (s)-1-boc-3-hydroxypiperidine
  • cis-4-amino-1-boc-3-hydroxypiperidine
  • Trans-4-amino-1-boc-3-hydroxypiperidine
  • 1-Boc-3-allyl-3-hydroxypiperidine
  • N,3,3-trimethyl-2-oxaspiro[4.5]decan-8-amine
  • 5-Methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
  • 1-[(5-bromo-1,3-thiazol-2-yl)methyl]-1H-1,2,3-triazol-4-amine
  • 3-chloro-4-(4-methanesulfonyl-1H-pyrazol-1-yl)aniline
  • rac-(3R,4S)-4-(3-methoxypropyl)pyrrolidin-3-ol
  • 2-{1-[(Tert-butoxy)carbonyl]-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl}acetic acid
  • 4-[(4-methanesulfonyl-1H-pyrazol-1-yl)methyl]aniline
  • 3-bromo-5-[(4-methanesulfonyl-1H-pyrazol-1-yl)methyl]aniline
  • 2-(3-fluorophenyl)-2-(4-methanesulfonyl-1H-pyrazol-1-yl)ethan-1-amine
  • [5-(2,2-Dimethylcyclopropyl)-1,2-oxazol-3-yl]methanethiol
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