TCN 201

Suppliers

Names

[ Name ]:
TCN 201

[Synonym ]:
Benzoic acid, 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-, 2-benzoylhydrazide
tcn 201
qcr-22
N-{4-[(2-Benzoylhydrazino)carbonyl]benzyl}-3-chloro-4-fluorobenzenesulfonamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₁H₁₇ClFN₃O₄S

[ Molecular Weight ]:
461.894

[ Exact Mass ]:
461.061218

[ PSA ]:
116.24000

[ LogP ]:
4.13

[ Index of Refraction ]:
1.625

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

Articles

Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices.

J. Pharmacol. Exp. Ther. 352(2) , 267-73, (2014)

Whereas ifenprodil has been used as a selective GluN1/GluN2B (NR1/NR2B, B-type) receptor antagonist to distinguish between GluN2B (NR2B) and GluN2A (NR2A)-containing N-methyl-d-aspartate receptors (NM...

PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors.

J. Neurosci. 35(2) , 776-85, (2015)

Severe autonomic dysfunction, including the loss of control of the cardiovascular, respiratory, and gastrointestinal systems, is a common comorbidity of stroke and other bleeding head injuries. Previo...

Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage.

J. Clin. Invest. 124(8) , 3645-55, (2014)

During brain ischemia, an excessive release of glutamate triggers neuronal death through the overactivation of NMDA receptors (NMDARs); however, the underlying pathways that alter glutamate homeostasi...

TCN 238
TCN 213
TCN 237 dihydrochloride
tcn
ONC-201 Dihydrochloride
YS-201
(5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)(piperidin-1-yl)methanone
N-(furan-2-ylmethyl)-3-methoxy-N-(tetrahydro-2H-pyran-4-yl)benzamide
(1s,3s)-Adamantan-1-yl(3-((dimethylamino)methyl)-1,4-thiazepan-4-yl)methanone
5-Chloro-2-(difluoromethyl)toluene
(1-(5-Nitrobenzo[d]thiazol-2-yl)piperidin-3-yl)methanol
(3-((Dimethylamino)methyl)-1,4-thiazepan-4-yl)(thiophen-3-yl)methanone
3-Benzyl-8-(trifluoromethyl)-3,4-dihydropyrimido[2,1-b][1,3,5]thiadiazin-6(2H)-one
2-(4-Methoxyphenyl)-6-methyl-1,3-diazinane-4-thione
N1,5-Dimethylbenzene-1,2,4-triamine
N-ethyl-N-(imidazo[1,2-a]pyridin-3-ylmethyl)-7-methoxybenzofuran-2-carboxamide

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