2',3'-Dideoxyguanosine

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Names

[ CAS No. ]:
85326-06-3

[ Name ]:
2',3'-Dideoxyguanosine

[Synonym ]:
2-amino-9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
2-amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-9H-purin-6-ol
2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-
MFCD00057074
2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
632.1ºC at 760 mmHg

[ Molecular Formula ]:
C10H13N5O3

[ Molecular Weight ]:
251.242

[ Flash Point ]:
336.1ºC

[ Exact Mass ]:
251.101837

[ PSA ]:
119.05000

[ LogP ]:
-0.73

[ Index of Refraction ]:
1.863

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xn

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(9-(5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
  • N-Isobutyrylguanosine
  • 2'-TBDMS-ibu-rG
  • Guanosine
  • 2-amino-9-((2R,5S)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
  • N2-isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine
  • 5'-O-(tert-butyldimethylsilyl)-N2-isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine
  • 5'-O-(tert-butyldimethylsilyl)-N2-isobutyryl-2',3'-O-thionocarbonylguanosine
  • 5'-O-(tert-butyldimethylsilyl)-N2-isobutyryl-2',3'-bis-O-[(methylthio)thiocarbonyl]guanosine
  • 5'-O-(tert-butyldimethylsilyl)-N2-isobutyryl-2',3'-bis-O-[[(β-cyanoethyl)thio]thiocarbonyl]guanosine

DownStream

  • Guanine

Related Compounds

  • 6-iodo-2',3'-dideoxyguanosine
  • 6-chloro-2',3'-dideoxyguanosine
  • 3'-Azido-2',3'-dideoxyguanosine
  • 2'-fluoro-2',3'-dideoxyguanosine
  • 2'-fluoro-2',3'-dideoxyguanosine
  • Carbocyclic-2',3'-dideoxyguanosine
  • 1-Phenyl-3-(prop-2-en-1-ylsulfanyl)-1,2-dihydropyrazin-2-one
  • 5-fluoro-N-(3-fluoro-4-methylphenyl)-3-methylpyridine-2-carboxamide
  • 1-methyl-4-(4-{[1-(1H-pyrazole-4-carbonyl)piperidin-4-yl]oxy}but-2-yn-1-yl)piperazine
  • 2-tert-butyl-1-[1-(oxane-4-carbonyl)azetidin-3-yl]-1H-1,3-benzodiazole
  • N-[3-(difluoromethoxy)phenyl]-3-fluoro-5-methylpyridine-2-carboxamide
  • N-(3-chloro-4-methoxyphenyl)-5-fluoro-6-methylpyridine-2-carboxamide
  • 1-Methyl-4-(4-{[1-(1,2,3,4-tetrahydronaphthalene-1-carbonyl)piperidin-4-yl]oxy}but-2-yn-1-yl)piperazine
  • 6-methyl-N-{4-[(trifluoromethyl)sulfanyl]phenyl}pyrazine-2-carboxamide
  • 3-(2,5-dimethoxyphenyl)-N-[(6-hydroxy-1,4-dithiepan-6-yl)methyl]-1-methyl-1H-pyrazole-5-carboxamide
  • N-[(4-bromophenyl)methyl]-5-fluoro-3-methylpyridine-2-carboxamide
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