Tedizolid

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Names

[ CAS No. ]:
856866-72-3

[ Name ]:
Tedizolid

[Synonym ]:
(5R)-3-{3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
Torezolid
TR-701
(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
TR-700
(R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one
Tedizolid [USAN:INN]
2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-, (5R)-
UNII:97HLQ82NGL
Tedizolid
(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-2-oxazolidinone

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
614.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H15FN6O3

[ Molecular Weight ]:
370.338

[ Flash Point ]:
325.4±34.3 °C

[ Exact Mass ]:
370.118958

[ PSA ]:
106.26000

[ LogP ]:
1.56

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.725

Safety Information

[ HS Code ]:
29339900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]carbamic acid phenylmethyl ester
  • (R)-Glycidyl butyrate
  • 2,5-Dibromopyridine
  • 5-Bromo-2-cyanopyridine

DownStream

Related Compounds

  • Tedizolid
  • (S)-Tedizolid
  • Tedizolid IMpurity
  • Tedizolid Phosphate
  • Tedizolid Impurity 39
  • Tedizolid Impurity 36
  • N-(8-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-YL)-1H-indole-6-carboxamide
  • 5-Cyclopropoxy-2-methylisonicotinonitrile
  • N-[3-(acetylamino)phenyl]-2-(7,8-dimethoxy-2-oxo-1,2-dihydro-3H-3-benzazepin-3-yl)acetamide
  • 3-(7-methoxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)-N-(1-methyl-1H-indol-4-yl)propanamide
  • 5-Cyclopropoxy-2-(dimethylamino)isonicotinonitrile
  • 2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-[3-(2-methylpropyl)-4-oxo-3,4-dihydroquinazolin-6-yl]acetamide
  • 5-Amino-2-cyclopropoxybenzonitrile
  • 4-Cyano-5-cyclopropoxy-N,N-dimethylpicolinamide
  • 2-Tert-butyl-5-cyclopropoxyisonicotinonitrile
  • 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone O-[(4-chlorophenyl)methyl]oxime
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