(-)-Blebbistatin

Suppliers

Names

[ CAS No. ]:
856925-71-8

[ Name ]:
(-)-Blebbistatin

[Synonym ]:
(3aS)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a,4a,8a-hexahydro-4H-pyrrolo[2,3-b]quinolin-4-one
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a,4a,8a-hexahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-
(3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
486.7±55.0 °C at 760 mmHg

[ Melting Point ]:
210-212ºC

[ Molecular Formula ]:
C18H16N2O2

[ Molecular Weight ]:
292.33

[ Flash Point ]:
248.1±31.5 °C

[ PSA ]:
52.90000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.681

[ Storage condition ]:
Desiccate at +4°C

[ Water Solubility ]:
DMSO: soluble5mg/mL

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H317-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1.

J. Physiol. 593(3) , 645-56, (2015)

Rac1 regulates stretch-stimulated (i.e. mechanical stress) glucose transport in muscle. Actin depolymerization decreases stretch-induced glucose transport in skeletal muscle. Rac1 is a required part o...

Formation of contractile networks and fibers in the medial cell cortex through myosin-II turnover, contraction, and stress-stabilization.

Cytoskeleton (Hoboken.) 72(1) , 29-46, (2015)

The morphology of adhered cells depends crucially on the formation of a contractile meshwork of parallel and cross-linked fibers along the contacting surface. The motor activity and minifilament assem...

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.

FASEB J. 24 , 4378-95, (2010)

Connexin-assembled gap junctions (GJs) and hemichannels coordinate intercellular signaling processes. Although the regulation of connexins in GJs has been well characterized, the molecular determinant...


More Articles


Related Compounds

  • (S)-(-)-Blebbistatin
  • (S)-(-)-Blebbistatin O-Benzoate
  • (+)-Blebbistatin
  • para-amino-Blebbistatin
  • (R)-(+)-Blebbistatin O-Benzoate
  • (S)-3'-hydroxy Blebbistatin
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine