(-)-Blebbistatin

Suppliers

Names

[ Name ]:
(-)-Blebbistatin

[Synonym ]:
(3aS)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a,4a,8a-hexahydro-4H-pyrrolo[2,3-b]quinolin-4-one
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a,4a,8a-hexahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-
(3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
486.7±55.0 °C at 760 mmHg

[ Melting Point ]:
210-212ºC

[ Molecular Formula ]:
C₁₈H₁₆N₂O₂

[ Molecular Weight ]:
292.33

[ Flash Point ]:
248.1±31.5 °C

[ PSA ]:
52.90000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.681

[ Storage condition ]:
Desiccate at +4°C

[ Water Solubility ]:
DMSO: soluble5mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H317-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1.

J. Physiol. 593(3) , 645-56, (2015)

Rac1 regulates stretch-stimulated (i.e. mechanical stress) glucose transport in muscle. Actin depolymerization decreases stretch-induced glucose transport in skeletal muscle. Rac1 is a required part o...

Formation of contractile networks and fibers in the medial cell cortex through myosin-II turnover, contraction, and stress-stabilization.

Cytoskeleton (Hoboken.) 72(1) , 29-46, (2015)

The morphology of adhered cells depends crucially on the formation of a contractile meshwork of parallel and cross-linked fibers along the contacting surface. The motor activity and minifilament assem...

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.

FASEB J. 24 , 4378-95, (2010)

Connexin-assembled gap junctions (GJs) and hemichannels coordinate intercellular signaling processes. Although the regulation of connexins in GJs has been well characterized, the molecular determinant...

(S)-(-)-Blebbistatin
(S)-(-)-Blebbistatin O-Benzoate
(+)-Blebbistatin
para-amino-Blebbistatin
(R)-(+)-Blebbistatin O-Benzoate
(S)-3'-hydroxy Blebbistatin
3-methoxy-N-propylbenzene-1-sulfonamide
4-methyl-3-[(2S)-oxiran-2-yl]pyridine
Benzoic acid, 2-[(1-oxo-3-phenyl-2-propen-1-yl)thio]-
N-[Cyano-(2,4-difluorophenyl)methyl]-3-hydroxypyridine-2-carboxamide
5-bromo-N-[cyano(cyclopropyl)methyl]-2-hydroxy-6-methylpyridine-3-carboxamide
Methyl 3-(1,1-dimethylethyl)-5-formyl-4-hydroxybenzoate
N-methoxy-N-methyl-2-(6-nitropyridin-2-yl)acetamide
Methyl 3-(2-amino-9H-purin-9-yl)propanoate
Methyl 2-amino-7H-purine-7-propanoate
Methyl 2-(iodomethyl)furan-3-carboxylate

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