1-(4-p-Fluorophenyl-4-hydroxybutyl)-4-o-methoxy-phenylpiperazine

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Names

[ CAS No. ]:
857-62-5

[ Name ]:
1-(4-p-Fluorophenyl-4-hydroxybutyl)-4-o-methoxy-phenylpiperazine

[Synonym ]:
4-fluorobenzoyltrifluoroacetone

Chemical & Physical Properties

[ Molecular Formula ]:
C21H27FN2O2

[ Molecular Weight ]:
358.45000

[ Exact Mass ]:
358.20600

[ PSA ]:
35.94000

[ LogP ]:
3.47300

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DO9155000
CHEMICAL NAME :
Benzyl alcohol, alpha-(3-(4-(o-methoxyphenyl)-1-piperazinyl)propyl)-p -fluoro-
CAS REGISTRY NUMBER :
857-62-5
BEILSTEIN REFERENCE NO. :
0711238
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H27-F-N2-O2
MOLECULAR WEIGHT :
358.50
WISWESSER LINE NOTATION :
T6N DNTJ A3YQR DF& DR BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#11366

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Fluorobenzaldehyde
  • 1‐(4‐fluorophenyl)‐but‐3‐en‐1‐ol
  • 1‐[1‐(benzyloxy)‐but‐3‐enyl]‐4‐fluorobenzene
  • 4-(benzyloxy)-4-(4-fluorophenyl)-butanal

DownStream

  • fluanisone

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • Rac-(1R,3R,5R)-3-aminobicyclo[3.1.0]hexane-1-carboxylic acid hydrochloride
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide