Phensuximide
Suppliers
Names
[ CAS No. ]:
86-34-0
[ Name ]:
Phensuximide
[Synonym ]:
1-methyl-3-phenyl-pyrrolidine-2,5-dione
1-methyl-3-phenylsuccinimide
Milontin
Lifen
Mirotin
Lifene
Mirontin
1-Methyl-3-phenyl-pyrrolidin-2,5-dion
Milonton
Epimal
Epimid
N-methylphenylsuccinimide
PM 334
Chemical & Physical Properties
[ Density]:
1.1596 (rough estimate)
[ Boiling Point ]:
324.47°C (rough estimate)
[ Melting Point ]:
71-73°
[ Molecular Formula ]:
C11H11NO2
[ Molecular Weight ]:
189.21100
[ Exact Mass ]:
189.07900
[ PSA ]:
37.38000
[ LogP ]:
1.09680
[ Index of Refraction ]:
1.5012 (estimate)
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WN3325000
- CHEMICAL NAME :
- Succinimide, N-methyl-2-phenyl-
- CAS REGISTRY NUMBER :
- 86-34-0
- BEILSTEIN REFERENCE NO. :
- 0155329
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C11-H11-N-O2
- MOLECULAR WEIGHT :
- 189.23
- WISWESSER LINE NOTATION :
- T5VNVTJ B1 DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 485 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 795 mg/kg/7D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - proteinuria Kidney, Ureter, Bladder - hematuria Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 666 mg/kg
- SEX/DURATION :
- female 8-10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 1533 mg/kg
- SEX/DURATION :
- female 8-10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Human Leukocyte
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 116,867,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4457 No. of Facilities: 46 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 279 (estimated) No. of Female Employees: 46 (estimated)
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%