7-Chloro-4-hydroxy-3-quinolinecarboxylic acid

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Names

[ CAS No. ]:
86-47-5

[ Name ]:
7-Chloro-4-hydroxy-3-quinolinecarboxylic acid

[Synonym ]:
7-Chloro-4-hydroxy-3-quinolinecarboxylic acid
7-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-
7-chloro-4-hydroxy quinoline-3-carboxylic acid
EINECS 201-673-5
MFCD00038080

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
416.5±45.0 °C at 760 mmHg

[ Melting Point ]:
250 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H6ClNO3

[ Molecular Weight ]:
223.613

[ Flash Point ]:
205.7±28.7 °C

[ Exact Mass ]:
223.003616

[ PSA ]:
70.42000

[ LogP ]:
4.20

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.732

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VB1950000
CHEMICAL NAME :
3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-
CAS REGISTRY NUMBER :
86-47-5
BEILSTEIN REFERENCE NO. :
0171561
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H6-Cl-N-O3
MOLECULAR WEIGHT :
223.62
WISWESSER LINE NOTATION :
T66 BNJ DVQ EQ IG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VB1950000

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl 7-chloro-4-hydroxy-3-quinolinecarboxylate
  • Propanedioic acid,2-[[(3-chlorophenyl)amino]methylene]-, 1,3-diethyl ester
  • 3-Quinolinecarbonitrile, 7-chloro-4-hydroxy-
  • 3-Chloroaniline

DownStream

  • 7-chloroquinolin-4-ol
  • 4,7-Dichloroquinoline
  • 1,2-Ethanediamine,N1-(7-chloro-4-quinolinyl)-
  • Chloroquine

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

4, 7-Dichloroquinoline. Price CC and Roberts RM.

Organic Synth. , 38-38, (1955)


More Articles

Related Compounds

  • 7-Chloro-4-hydroxy-3-quinolinecarboxylic acid
  • 6-Chloro-4-hydroxy-3-quinolinecarboxylic acid
  • 8-Chloro-4-hydroxy-3-quinolinecarboxylic acid
  • Ethyl 7-chloro-4-hydroxy-3-quinolinecarboxylate
  • 7-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid
  • 7-Chloro-4-hydroxy-6-iodo-quinoline-3-carboxylic acid ethyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1,4-Diazabicyclo[2.2.2]octane-2-carboxamide, N-[3-(difluoromethyl)phenyl]-5-methyl-
  • Ethyl 6-[(prop-2-yn-1-yloxy)amino]pyridine-3-carboxylate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine