naphthoic acid

Names

[ CAS No. ]:
86-55-5

[ Name ]:
naphthoic acid

[Synonym ]:
EINECS 201-681-9
1-Naphthoic acid
1-Naphthylcarboxylic acid
naphthalene-1-carboxylic acid
naphthoic acid
α-Naphthoic acid
MFCD00004007
1-Naphthalenecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
300.0±0.0 °C at 760 mmHg

[ Melting Point ]:
157-160 °C(lit.)

[ Molecular Formula ]:
C₁₁H₈O₂

[ Molecular Weight ]:
172.18

[ Flash Point ]:
164.6±13.9 °C

[ Exact Mass ]:
172.052429

[ PSA ]:
37.30000

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.673

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL0960000

CHEMICAL NAME :: 1-Naphthoic acid

CAS REGISTRY NUMBER :: 86-55-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H8-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-143766

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25-S37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
QL0960000

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Naphthylmethanol
carbon monoxide
1-Bromonaphthalene
Carbon dioxide
1-Naphthaleneboronic acid neopentyl glycol cyclic ester
1-Methylnaphthalene
Naphthalene
1-Iodonaphthalene
Lithium formate

DownStream

1-chloro-3-hydroxypropan-2-yl 1-naphthoate
(3-chloro-2-hydroxypropyl) naphthalene-1-carboxylate
5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid
1,2,3,4-Tetrahydronaphthalene-1-carboxylic acid
5-Bromonaphthalen-1-amine
1-naphthhydrazide
1-Naphthylmethanol
1-Iodonaphthalene
Naphthalene
1,2,3,4-Tetrahydronaphthalene

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Theoretical study of the nuO-H IR spectra for the hydrogen bond dimers from the polarized spectra of glutaric and 1-naphthoic acid crystals: Fermi resonances effects.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(1) , 58-66, (2009)

A full quantum theoretical model is proposed to study the nu(O-H) experimental IR line shapes of polarized crystalline glutaric and 1-naphthoic acid dimer crystals at room and liquid nitrogen temperat...

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy.

Oncotarget 6 , 13671-87, (2015)

Herein, we evaluated the anti-cancer effect and molecular mechanisms of a novel betulinic acid (BA) derivative, SYK023, by using two mouse models of lung cancer driven by KrasG12D or EGFRL858R. We fou...

A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04.

FEMS Microbiol. Lett. 320(2) , 128-34, (2011)

The chrysene-degrading bacterium Pseudoxanthomonas sp. PNK-04 was isolated from a coal sample. Three novel metabolites, hydroxyphenanthroic acid, 1-hydroxy-2-naphthoic acid and salicylic acid, were id...