Fmoc-Cys(Acm)-OH

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Names

[ CAS No. ]:
86060-81-3

[ Name ]:
Fmoc-Cys(Acm)-OH

[Synonym ]:
(2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine
MFCD00038769
L-Cysteine, S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
714.1±60.0 °C at 760 mmHg

[ Melting Point ]:
147-150 °C

[ Molecular Formula ]:
C21H22N2O5S

[ Molecular Weight ]:
414.475

[ Flash Point ]:
385.7±32.9 °C

[ Exact Mass ]:
414.124939

[ PSA ]:
130.03000

[ LogP ]:
3.92

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.618

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methylN-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(acetamidomethyl)-L-cysteinate
  • H-Cys(Acm)-OH.H20
  • 9-Fluorenylmethyl chloroformate
  • 9H-fluoren-9-ylmethyl N-diazocarbamate
  • (R)-3-((acetamidomethyl)thio)-2-aminopropanoic acid compound with trifluoromethanesulfonic acid (1:1)

DownStream

  • Fmoc-Cys(Acm)-OPfp

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The investigation of Fmoc-cysteine derivatives in solid phase peptide synthesis.

Pept. Res. 2(1) , 147-52, (1989)

Fmoc-Cys(t-Bu)-OH, Fmoc-Cys(Acm)-OH, and Fmoc-Cys(Trt)-OH exhibit excellent synthesis characteristics when used in Fmoc solid phase peptide synthesis on the Applied Biosystems Model 431A peptide synth...


More Articles

Related Compounds

  • Fmoc-Cys(Acm)-OH;; N-Fmoc-S-Acetamidomethyl-L-Cysteine
  • Fmoc-Cys(Acm)-OPfp
  • Fmoc-Cys(Acm)-ol
  • (Fmoc-Cys-OH)2
  • boc-cys(acm)-oh
  • H-Cys(Acm)-OH HCl
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-[4-[4-(Methoxymethyl)-4-methylpiperidine-1-carbonyl]phenyl]prop-2-enamide
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide