Butanedioic acid, mono[5- (3,4-dichlorophenyl)-2,3-dihydro-6, 7-bis[[[[(1-methylethyl)amino]carbonyl]oxy]methyl]-1H-pyrrolizin-2-yl] ester, (R)-, compd. with N,N-dimethyl-4-pyridinamine (1:1)

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Names

[ Name ]:
Butanedioic acid, mono[5- (3,4-dichlorophenyl)-2,3-dihydro-6, 7-bis[[[[(1-methylethyl)amino]carbonyl]oxy]methyl]-1H-pyrrolizin-2-yl] ester, (R)-, compd. with N,N-dimethyl-4-pyridinamine (1:1)

[Synonym ]:
cha-221

Chemical & Physical Properties

[ Boiling Point ]:
774.6ºC at 760 mmHg

[ Molecular Formula ]:
C₃₄H₄₃Cl₂N₅O₈

[ Molecular Weight ]:
720.64000

[ Flash Point ]:
422.3ºC

[ Exact Mass ]:
719.24900

[ PSA ]:
161.32000

[ LogP ]:
6.99320

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Succinic anhydride
4-Dimethylaminopyridine
Carbamic acid,(1-methylethyl)-,[5-(3,4-dichlorophenyl)-2,3-dihydro-2-hydroxy-1H-pyrrolizine-6,7-diyl]bis(methylene)ester, (R)- (9CI)
2-O-(tert-butyldimethylsilyl)-5-(3,4-dichlorophenyl)-6,7-bis(hydroxymethyl)-2,3-dihydro-1H-pyrrolizine bis(2-propylcarbamate)

DownStream

Related Compounds

N-allyl-1-(1-isopropylpiperidin-4-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
N-isopentyl-1-(1-isopropylpiperidin-4-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
N-cyclopentyl-1-(1-isopropylpiperidin-4-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
1-(1-isopropylpiperidin-4-yl)-5-methyl-N-pentyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
3-methyl-N-(3-(6-oxopyridazin-1(6H)-yl)propyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
(3-(1H-tetrazol-1-yl)phenyl)(3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone
(2-phenyl-2H-1,2,3-triazol-4-yl)(3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone
(2-Methylthiazol-4-yl)(3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone
(3-(furan-2-yl)-1H-pyrazol-5-yl)(3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone
Benzo[d]thiazol-6-yl(3-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone