N-(Phenoxyacetyl)deacetylcolchicine
Suppliers
Names
[ CAS No. ]:
86436-45-5
[ Name ]:
N-(Phenoxyacetyl)deacetylcolchicine
[Synonym ]:
2-Phenoxy-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
N-(Phenoxyacetyl)deacetylcolchicine
Acetamide,2-phenoxy-N-(5,6,7,9-tetrahydro-9-oxo-1,2,3,10-tetramethoxybenzo(a)heptalen-7-yl)-,(S)
Chemical & Physical Properties
[ Density]:
1.28g/cm3
[ Boiling Point ]:
807.8ºC at 760 mmHg
[ Molecular Formula ]:
C28H29NO7
[ Molecular Weight ]:
491.53200
[ Flash Point ]:
442.3ºC
[ Exact Mass ]:
491.19400
[ PSA ]:
92.32000
[ LogP ]:
4.32160
[ Index of Refraction ]:
1.612
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC7670000
- CHEMICAL NAME :
- Acetamide, 2-phenoxy-N-(5,6,7,9-tetrahydro-9-oxo-1,2,3,10-tetram ethoxybenzo(a)heptale n- 7-yl)-, (S)-
- CAS REGISTRY NUMBER :
- 86436-45-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C28-H29-N-O7
- MOLECULAR WEIGHT :
- 491.58
- WISWESSER LINE NOTATION :
- T B677 MV&T&J CO1 DO1 EO1 JMV1OR& NO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983