2-Hydroxy-6-methylisonicotinic acid

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Names

[ Name ]:
2-Hydroxy-6-methylisonicotinic acid

[Synonym ]:
4-Pyridinecarboxylic acid, 1,2-dihydro-6-methyl-2-oxo-
6-Methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid
MFCD02682019
2-methyl-6-oxo-1H-pyridine-4-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
489.9±45.0 °C at 760 mmHg

[ Melting Point ]:
330ºC

[ Molecular Formula ]:
C₇H₇NO₃

[ Molecular Weight ]:
153.135

[ Flash Point ]:
250.1±28.7 °C

[ Exact Mass ]:
153.042587

[ PSA ]:
70.42000

[ LogP ]:
-0.03

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.608

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl 3-cyano-6-methyl-2-oxo-1H-pyridine-4-carboxylate
Ethyl acetopyruvate
Methyl acetylpyruvate
4-Pyridinecarboxylicacid, 3-cyano-1,2-dihydro-6-methyl-2-oxo-, ethyl ester
4-Pyridinecarboxylic acid, 3-cyano-1,2-dihydro-6-methyl-2-oxo

DownStream

Methyl 2-chloro-6-picoline-4-carboxylate
2-chloro-6-methylpyridine-4-carbohydrazide
Methyl 2-hydroxy-6-methylpyridine-4-carboxylate
2-Methylisonicotinic acid
Methyl 2-methylisonicotinate
2-Chloro-6-methylisonicotinic acid
2-CHLORO-6-METHYLPYRIDINE-4-CARBONYLCHLORIDE
4-Pyridinecarboxylicacid, 2-methyl-, hydrazide

Related Compounds

2-Hydroxy-6-methylbenzenesulfonic acid
2-hydroxy-6-trifluoromethylbenzoic acid methyl ester
2-Hydroxy-6-methoxybenzoic acid
2-hydroxy-6-phenylmethoxybenzoic acid
2-hydroxy-6-methoxyhexanoic acid
2-hydroxy-6-nonylbenzenesulfonic acid
2-((6-(hydroxymethyl)-2-(2-methoxyphenyl)-9-methyl-5H-pyrido[4',3':5,6]pyrano[2,3-d]pyrimidin-4-yl)thio)-N-phenylacetamide
2-((2-(2-fluorophenyl)-6-(hydroxymethyl)-9-methyl-5H-pyrido[4',3':5,6]pyrano[2,3-d]pyrimidin-4-yl)thio)-N-mesitylacetamide
N-(3,5-dimethylphenyl)-2-((2-(2-fluorophenyl)-6-(hydroxymethyl)-9-methyl-5H-pyrido[4',3':5,6]pyrano[2,3-d]pyrimidin-4-yl)thio)acetamide
2-((2-(4-ethylphenyl)-5-(4-fluorophenyl)-1H-imidazol-4-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide
Ethyl 1-(3-((3,4-dimethylphenyl)sulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl)piperidine-4-carboxylate
N-(4-ethoxyphenyl)-3-[(4-ethylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine
4-(4-chlorobenzyl)-2-(2-methoxyphenyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide
2-((3-(4-ethoxyphenyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)-N-(3-methoxyphenyl)acetamide
2-(6-ethyl-3-((4-ethylphenyl)sulfonyl)-4-oxoquinolin-1(4H)-yl)-N-(p-tolyl)acetamide
N-((Benzyloxy)carbonyl)-N-cyclopentylglycine

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