2-Hydroxy-6-methylisonicotinic acid

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Names

[ CAS No. ]:
86454-13-9

[ Name ]:
2-Hydroxy-6-methylisonicotinic acid

[Synonym ]:
4-Pyridinecarboxylic acid, 1,2-dihydro-6-methyl-2-oxo-
6-Methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid
MFCD02682019
2-methyl-6-oxo-1H-pyridine-4-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
489.9±45.0 °C at 760 mmHg

[ Melting Point ]:
330ºC

[ Molecular Formula ]:
C7H7NO3

[ Molecular Weight ]:
153.135

[ Flash Point ]:
250.1±28.7 °C

[ Exact Mass ]:
153.042587

[ PSA ]:
70.42000

[ LogP ]:
-0.03

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.608

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 3-cyano-6-methyl-2-oxo-1H-pyridine-4-carboxylate
  • Ethyl acetopyruvate
  • Methyl acetylpyruvate
  • 4-Pyridinecarboxylicacid, 3-cyano-1,2-dihydro-6-methyl-2-oxo-, ethyl ester
  • 4-Pyridinecarboxylic acid, 3-cyano-1,2-dihydro-6-methyl-2-oxo

DownStream

  • Methyl 2-chloro-6-picoline-4-carboxylate
  • 2-chloro-6-methylpyridine-4-carbohydrazide
  • Methyl 2-hydroxy-6-methylpyridine-4-carboxylate
  • 2-Methylisonicotinic acid
  • Methyl 2-methylisonicotinate
  • 2-Chloro-6-methylisonicotinic acid
  • 2-CHLORO-6-METHYLPYRIDINE-4-CARBONYLCHLORIDE
  • 4-Pyridinecarboxylicacid, 2-methyl-, hydrazide

Related Compounds

  • 2-Hydroxy-6-methylbenzenesulfonic acid
  • 2-hydroxy-6-trifluoromethylbenzoic acid methyl ester
  • 2-Hydroxy-6-methoxybenzoic acid
  • 2-hydroxy-6-phenylmethoxybenzoic acid
  • 2-hydroxy-6-methoxyhexanoic acid
  • 2-hydroxy-6-nonylbenzenesulfonic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine