3,3-dichloro-4,5-dihydro-1H-1-benzazepin-2-one

Names

[ CAS No. ]:
86499-22-1

[ Name ]:
3,3-dichloro-4,5-dihydro-1H-1-benzazepin-2-one

[Synonym ]:
3,3-dichloro-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
2H-1-Benzazepin-2-one,3,3-dichloro-1,3,4,5-tetrahydro
3,3-dichloro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C10H9Cl2NO

[ Molecular Weight ]:
230.09100

[ Exact Mass ]:
229.00600

[ PSA ]:
32.59000

[ LogP ]:
2.83030

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,5-Dihydro-1H-benzo[b]azepin-2(3H)-one
  • sodium carbonate

DownStream

  • 3-Chloro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
  • benazeprilat
  • Benazepril hydrochloride
  • Benazepril hydrochloride

Related Compounds

  • 3,3-dichloro-1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
  • 3-amino-9-fluoro-1,3,4,5-tetrahydro-1-benzazepin-2-one,oxalic acid
  • 3-(3,4,5-trimethoxyphenyl)-2,5-dihydro-1H-1,2,4-triazin-6-one
  • 2,3,4,5-Tetrahydro-1-[(2-imidazolin-2-yl)methyl]-1H-1-benzazepin-2-one
  • 2,3,4,5-Tetrahydro-1-[2-(dimethylamino)ethyl]-1H-1-benzazepin-2-one
  • 2,3,4,5-Tetrahydro-1-[2-(diisopropylamino)ethyl]-1H-1-benzazepin-2-one
  • 1-(2-Bromoethyl)-2-methylpiperazine
  • (R)-2-(tert-Butoxycarbonyl)-6-oxa-2-azaspiro[3.4]octane-8-carboxylic acid
  • Rel-ethyl (7S,8S)-7-methyl-1,4-dioxaspiro[4.5]decane-8-carboxylate
  • 1-Benzyl 2-methyl (2S,4S)-4-hydroxy-2-methylpyrrolidine-1,2-dicarboxylate
  • Benzyl (2R,4S)-4-((tert-butyldimethylsilyl)oxy)-2-(4-(methoxycarbonyl)phenyl)piperidine-1-carboxylate
  • (R)-2-(Pyrrolidin-2-yl)-3-(trifluoromethyl)benzoic acid
  • (S)-8-(tert-Butoxycarbonyl)-3,3-difluoro-8-azaspiro[4.5]decane-1-carboxylic acid
  • rac-(2R,3S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-(3-methoxyphenyl)pyrrolidine-3-carboxylic acid, cis
  • tert-Butyl ((3S,4R)-4-hydroxypyrrolidin-3-yl)(methyl)carbamate
  • (5-Cyclopropyl-2-ethoxy-4-(methylsulfonyl)phenyl)methanol