3,3-dichloro-4,5-dihydro-1H-1-benzazepin-2-one

Names

[ CAS No. ]:
86499-22-1

[ Name ]:
3,3-dichloro-4,5-dihydro-1H-1-benzazepin-2-one

[Synonym ]:
3,3-dichloro-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
2H-1-Benzazepin-2-one,3,3-dichloro-1,3,4,5-tetrahydro
3,3-dichloro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

Chemical & Physical Properties

[ Molecular Formula ]:
C10H9Cl2NO

[ Molecular Weight ]:
230.09100

[ Exact Mass ]:
229.00600

[ PSA ]:
32.59000

[ LogP ]:
2.83030

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,5-Dihydro-1H-benzo[b]azepin-2(3H)-one
  • sodium carbonate

DownStream

  • 3-Chloro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
  • benazeprilat
  • Benazepril hydrochloride
  • Benazepril hydrochloride

Related Compounds

  • 3,3-dichloro-1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
  • 3-amino-9-fluoro-1,3,4,5-tetrahydro-1-benzazepin-2-one,oxalic acid
  • 3-(3,4,5-trimethoxyphenyl)-2,5-dihydro-1H-1,2,4-triazin-6-one
  • 2,3,4,5-Tetrahydro-1-[(2-imidazolin-2-yl)methyl]-1H-1-benzazepin-2-one
  • 2,3,4,5-Tetrahydro-1-[2-(dimethylamino)ethyl]-1H-1-benzazepin-2-one
  • 2,3,4,5-Tetrahydro-1-[2-(diisopropylamino)ethyl]-1H-1-benzazepin-2-one
  • 8-[(1R,5S,6R)-6-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-cyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one
  • 1-ethyl-6-methoxy-4-oxo-N-(2-phenylethyl)-1,4-dihydroquinoline-3-carboxamide
  • Propanedioic acid, 2,2-difluoro-, 1-ethyl ester
  • 4-butoxy-3-methyl-N-(3-methylpyridin-2-yl)benzene-1-sulfonamide
  • [(2,4-Dichloro-5-methylphenyl)sulfonyl](2-methoxyethyl)amine
  • 5-amino-1-(3-bromophenyl)-N-isopropyl-1H-1,2,3-triazole-4-carboxamide
  • 5-amino-1-(4-bromophenyl)-N-methyl-N-phenyl-1H-1,2,3-triazole-4-carboxamide
  • 1-[(4-Chloro-3-pentyloxyphenyl)sulfonyl]piperidine-4-carboxamide
  • 5-amino-N-isopropyl-1-(o-tolyl)-1H-1,2,3-triazole-4-carboxamide
  • N,N,4,5-tetramethyl-2-propoxybenzene-1-sulfonamide
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