FR 180204

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Names

[ CAS No. ]:
865362-74-9

[ Name ]:
FR 180204

[Synonym ]:
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine
2H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-
FR 180204

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C18H13N7

[ Molecular Weight ]:
327.343

[ Exact Mass ]:
327.123230

[ PSA ]:
98.51000

[ LogP ]:
0.29

[ Appearance of Characters ]:
faint yellow to dark yellow

[ Index of Refraction ]:
1.846

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: ≥10mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-20

[ Safety Phrases ]:
20/21

[ RIDADR ]:
NONH for all modes of transport

Articles

Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase.

Biol. Pharm. Bull. 38 , 1809-16, (2015)

Orthovanadate (OVA), a protein tyrosine phosphatase inhibitor, induces vasoconstriction in a Rho kinase-dependent manner. The aim of this study was to determine the mechanism underlying OVA-induced va...

Sequential phosphorylation analysis using dye-tethered peptides and microfluidic isoelectric focusing electrophoresis.

Biosens. Bioelectron. 73 , 93-9, (2015)

We report a simple method for analyzing sequential phosphorylation by protein kinases using fluorescent peptide substrates and microfluidic isoelectric focusing (μIEF) electrophoresis. When a dye-labe...

Saturated free fatty acids induce cholangiocyte lipoapoptosis.

Hepatology 60(6) , 1942-56, (2014)

Recent studies have identified a cholestatic variant of nonalcoholic fatty liver disease (NAFLD) with portal inflammation and ductular reaction. Based on reports of biliary damage, as well as increase...


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Related Compounds

  • FR-188582
  • FR 167653
  • fr 165649
  • FR 171113
  • FR 58664
  • FR-295389
  • 4-(azetidin-3-yloxy)-3,5-dimethyl-1-(propan-2-yl)-1H-pyrazole
  • 2-(But-3-yn-2-yl)-4-fluoro-1-methoxybenzene
  • {2,2-dimethyl-3-[6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]cyclopropyl}methanamine
  • rac-[(1R,2R)-2-[4-methoxy-3-(trifluoromethyl)phenyl]cyclopropyl]methanamine
  • {1-[(3,5-Dichloropyridin-4-yl)methyl]cyclopropyl}methanamine
  • 1-Bromo-3-(2-isocyanatoethyl)-5-nitrobenzene
  • Tert-butyl 2-(2-methylfuran-3-yl)piperazine-1-carboxylate
  • 3-Amino-1-(2-{[(tert-butoxy)carbonyl]amino}-5-hydroxyphenyl)cyclobutane-1-carboxylic acid
  • (1R)-2,2,2-trifluoro-1-(1-methyl-1H-indol-5-yl)ethan-1-ol
  • tert-butyl N-[4-(3-amino-1,1,1-trifluoropropan-2-yl)-2-hydroxyphenyl]carbamate
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