1-Oxaspiro(4.5)dec-3-en-2-one, 4-((4-chlorophenyl)hydroxymethyl)-3-met hyl-

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Names

[ CAS No. ]:
86560-17-0

[ Name ]:
1-Oxaspiro(4.5)dec-3-en-2-one, 4-((4-chlorophenyl)hydroxymethyl)-3-met hyl-

[Synonym ]:
4-((4-Chlorophenyl)hydroxymethyl)-3-methyl-1-oxaspiro(4.5)dec-3-en-2-one
1-[(4-chlorophenyl)-hydroxymethyl]-2-methyl-4-oxaspiro[4.5]dec-1-en-3-one
1-Oxaspiro(4.5)dec-3-en-2-one,4-((4-chlorophenyl)hydroxymethyl)-3-methyl
4-Chlorohydroxybenzyl-3 methyl-2 cyclohexane spiro-4,4-butene-2 olide-4 [French]
4-Chlorohydroxybenzyl-3 methyl-2 cyclohexane spiro-4,4-butene-2 olide-4

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
521.2ºC at 760 mmHg

[ Molecular Formula ]:
C17H19ClO3

[ Molecular Weight ]:
306.78400

[ Flash Point ]:
269ºC

[ Exact Mass ]:
306.10200

[ PSA ]:
46.53000

[ LogP ]:
3.94960

[ Index of Refraction ]:
1.596

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP3675395
CHEMICAL NAME :
1-Oxaspiro(4.5)dec-3-en-2-one, 4-((4-chlorophenyl)hydroxymethyl)-3-methyl-
CAS REGISTRY NUMBER :
86560-17-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H19-Cl-O3
MOLECULAR WEIGHT :
306.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 18,147,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Oxaspiro(4.5)dec-3-en-2-one, 4-(4-chlorobenzoyl)-3-methyl-
  • 3-methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carbonyl chloride
  • Chlorobenzene

DownStream

Related Compounds

  • 1,5-dimethyl-N-{[5-methyl-1-(propan-2-yl)-1H-pyrazol-4-yl]methyl}-1H-pyrazol-4-amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(8-(Ethoxymethyl)-6-azaspiro[3.4]octan-6-yl)-2-(methylamino)ethan-1-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • [(1R,5R)-1-Bicyclo[3.1.0]hexanyl]methanol