diethyl trichloromethylphosphonate

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Names

[ CAS No. ]:
866-23-9

[ Name ]:
diethyl trichloromethylphosphonate

[Synonym ]:
trichloromethanephosphonic acid diethyl ester
diethyl 1,1,1-trichloromethylphosphonate
Methanephosphonic acid,trichloro-,diethyl ester
Phosphonic acid,trichloromethyl-,diethyl ester
MFCD00013666
Ro 3-0658
diethyl trichloromethanephosphonate

Chemical & Physical Properties

[ Density]:
1.362 g/mL at 25ºC(lit.)

[ Boiling Point ]:
126ºC (0.3 torr)

[ Molecular Formula ]:
C5H10Cl3O3P

[ Molecular Weight ]:
255.46400

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
253.94300

[ PSA ]:
45.34000

[ LogP ]:
3.58020

[ Appearance of Characters ]:
Liquid

[ Index of Refraction ]:
n20/D 1.463(lit.)

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TA0988000
CHEMICAL NAME :
Phosphonic acid, trichloromethyl-, diethyl ester
CAS REGISTRY NUMBER :
866-23-9
BEILSTEIN REFERENCE NO. :
1210640
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H10-Cl3-O3-P
MOLECULAR WEIGHT :
255.47
WISWESSER LINE NOTATION :
GXGGPO&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,20,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 10,121,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00008

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN3278

[ WGK Germany ]:
3

[ RTECS ]:
TA0988000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2931900090

Synthetic Route

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

I.M. Downie et al.

Tetrahedron 38 , 1457, (1982)

Addition of diethyl trichloromethylphosphonate to olefins catalysed by copper complexes. Villemin D, et al.

Tetrahedron Lett. 35(21) , 3537-38, (1994)

Photochemical type I and II elimination reactions of dialkyl (trichloromethyl) phosphonates. Suzuki N, et al.

Bull. Chem. Soc. Jpn. 53(5) , 1421-24, (1980)


More Articles


Related Compounds

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  • diethyl N-methylaminomethylphosphonate
  • diethyl 2-(1-ethylsulfanyl-2-methylpropyl)propanedioate
  • diethyl 1-cyano-1-(4-isobutylphenyl)ethylphosphate
  • diethyl 2-benzyl-2-pentylpropanedioate
  • Diethyl-(trimethylsilylamido)-phosphit
  • Ethyl 3-[5-methyl-1-(4-nitrophenyl)pyrazol-4-yl]-3-oxopropanoate
  • Tert-butyl (2-(2-(benzyloxy)phenyl)-2-hydroxyethyl)carbamate
  • 5-(2-Aminocyclopropyl)-2-fluorobenzonitrile
  • Ethanol,2,2'-[(1,7-diamino-1h-indazol-4-yl)imino]bis-
  • (2,4-Dibromophenyl)methanesulfonamide
  • 2-Amino-6-bromo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid hydrochloride
  • 5-(Propoxymethyl)-1,2,4-oxadiazole-3-carboxylic acid
  • B-(4-Chloro-2,3-dihydro-1-methyl-1H-indol-7-yl)boronic acid
  • TEPA,N-p-CL benzylidene-N-hydrazin-1-yl
  • 5-[1-(Dimethylamino)-2-methylpropan-2-yl]oxypyridin-2-amine
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