dorsomorphin

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Names

[ CAS No. ]:
866405-64-3

[ Name ]:
dorsomorphin

[Synonym ]:
Dorsomorphin
BML-275
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
Pyrazolo[1,5-a]pyrimidine, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-
Compound C
6-{4-[2-(1-Piperidinyl)ethoxy]phenyl}-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine
AMPK Inhibitor,Compound C

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C24H25N5O

[ Molecular Weight ]:
399.488

[ Exact Mass ]:
399.205902

[ PSA ]:
55.55000

[ LogP ]:
2.39

[ Index of Refraction ]:
1.670

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Regulation of insulin-like growth factor signaling by metformin in endometrial cancer cells.

Oncol. Lett. 8(5) , 1993-1999, (2014)

Obesity, diabetes and insulin resistance are marked risk factors that promote the development of type I endometrial cancer. Previous studies have demonstrated that insulin-like growth factor 1 (IGF-1)...

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML.

Autophagy 11 , 1114-29, (2015)

Autophagy is induced during differentiation of human monocytes into macrophages that is mediated by CSF1/CSF-1/M-CSF (colony stimulating factor 1 [macrophage]). However, little is known about the mole...

Alpha-lipoic acid activates eNOS through activation of PI3-kinase/Akt signaling pathway.

Vascul. Pharmacol. 64 , 28-35, (2015)

Lipoic acid (LA) exerts therapeutic effects on cardiovascular diseases. However, the mechanisms underlying these therapeutic effects remain elusive. Endothelial nitric oxide synthase (eNOS) plays a cr...


More Articles


Related Compounds

  • Dorsomorphin 2HCl
  • 4-(2-Methoxy-3-methylphenyl)butan-2-amine
  • 1-[2-(azetidin-2-yl)ethyl]-1H-pyrazole
  • 2-[2-(Methylsulfanyl)phenyl]propanenitrile
  • 2-(2-Methylquinolin-4-yl)butanoic acid
  • 4-(1H-imidazol-5-yl)-1,3-thiazol-2-amine
  • 4-Amino-4-(cyclohexylmethyl)cyclohexan-1-ol
  • 6-(tert-Butoxycarbonyl)hexahydropyrano[2,3-c]pyrrole-7a(2H)-carboxylic acid
  • 2-(6-Methylpyridin-3-yl)prop-2-en-1-amine
  • 3-(3-Methyl-4-nitrophenyl)propan-1-ol
  • 3-(but-3-yn-2-yl)-1-ethyl-1H-pyrazole
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