spirobromin

Suppliers

Names

[ CAS No. ]:
86641-76-1

[ Name ]:
spirobromin

[Synonym ]:
Spirobromin
Dibrospidium Chloride
chlorospirobromine
spirobromine

Chemical & Physical Properties

[ Molecular Formula ]:
C18H32Br2Cl2N4O2

[ Molecular Weight ]:
567.18600

[ Exact Mass ]:
564.02700

[ PSA ]:
40.62000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HM1157000
CHEMICAL NAME :
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-bromo-1-oxopropyl)-, dichloride
CAS REGISTRY NUMBER :
86641-76-1
LAST UPDATED :
198809
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H32-Br2-N4-O2.2Cl
MOLECULAR WEIGHT :
567.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
825 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1924 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dichloride
  • 3-Bromopropanoyl chloride

DownStream

  • 3-Bromopropanoic acid
  • 3-Chloropropionic Acid
  • 3,12-bis(3'-chloro-1'-oxopropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dibromide
  • 1-(12-prop-2-enoyl-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl)prop-2-en-1-one,tetrachloride,hydrate
  • 3,12-bis(3'-hydroxy-1'-oxopropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dichloride
  • Hydroxypropionic acid

Related Compounds

  • Spirobromin
  • 5-Tert-butoxycarbonyl-2,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-4-carboxylic acid
  • rac-ethyl 2-[(1R,5R,6S)-6-methoxy-2-azabicyclo[3.2.0]heptan-6-yl]acetate
  • rac-tert-butyl (2R,3aS,5R,6aS)-2-methyl-hexahydro-2H-furo[3,2-b]pyrrole-5-carboxylate
  • 5-{[(Tert-butoxy)carbonyl]amino}-6-(trifluoromethyl)pyridine-2-carboxylic acid
  • Methyl 2,2-difluoro-2-(3-methoxyazetidin-3-yl)acetate
  • 4-{[(Benzyloxy)carbonyl]amino}-6-cyclopropylpyrimidine-2-carboxylic acid
  • (2R)-2-({[(benzyloxy)carbonyl]amino}methyl)butanoic acid
  • 2-(3-{[(tert-butoxy)carbonyl]amino}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl)acetic acid
  • Methyl 4'-methyl-3'-oxaspiro[azetidine-3,2'-bicyclo[2.1.1]hexane]-1'-carboxylate
  • 1-{[(tert-butoxy)carbonyl]amino}-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid
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