Triethyl phosphonoacetate

Suppliers

Names

[ CAS No. ]:
867-13-0

[ Name ]:
Triethyl phosphonoacetate

[Synonym ]:
EINECS 212-757-6
Triethyl phosphonacetate
Triethyl phosphonoac
Triethyl phosphono acetate
(ETHOXYCARBONYLMETHYL)DIETHOXYPHOSPHINEOXIDE
AURORA KA-1452
diethyl ethoxycarbonylmethanephosphonate
Ethyl (diethoxyphosphoryl)acetate
ethyl diethoxyphosphorylacetate
MFCD00009177
PHOSPHONOACETIC ACID ETHYL ESTER
(ETHOXYCARBONYLMETHYL)-DIETHOXYPHOSPHINE OXIDE
TRIETHYL PHOSPHONACETIC ACID
diethoxyphosphoryl-acetic acid ethyl ester
TRIETHYLPHOSPHONEACETATE
TRIETHYLPHOSPHONOAETATE
Triethylphosphonoacetate
TRENBOLONE HEXAHYDROBENZYL CARBONATE
Acetic acid, 2-(diethoxyphosphinyl)-, ethyl ester
TRIETHYL PHOSPHONOACEATE
ethyl 2-(diethoxyphosphoryl)acetate
tl465
Triethyl Phosphonoacetate ( Tepp)
TRIETHYL PHOSPHONOACETATE FOR SYNTHESIS
Triethyl phosphonoacetate
TRIETHYLPHOSPONOACETATE
Diethylphosphonoacetic Acid Ethyl Ester
Trietyl Phosphonoacetate
phosphonoacetic acid triethyl ester
Diethyl [(ethoxycarbonyl)methyl]phosphonate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
287.4±23.0 °C at 760 mmHg

[ Melting Point ]:
-24°C

[ Molecular Formula ]:
C₈H₁₇O₅P

[ Molecular Weight ]:
224.19

[ Flash Point ]:
141.6±42.9 °C

[ Exact Mass ]:
224.081360

[ PSA ]:
71.64000

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.424

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AG9800000

CHEMICAL NAME :: Acetic acid, diethylphosphono-, ethyl ester

CAS REGISTRY NUMBER :: 867-13-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H17-O5-P

MOLECULAR WEIGHT :: 224.22

WISWESSER LINE NOTATION :: OPO&O&2&2&1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,15,1953

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1180 mg/m3/10M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,NOV1942

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38;R51/53

[ Safety Phrases ]:
S61-S37/39-S26

[ RIDADR ]:
UN 3082 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AG9800000

[ Hazard Class ]:
9.0

[ HS Code ]:
2931901990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

ethyl 2-bromoacetate
Triethyl phosphite
ethyl chloroacetate
Diethyl phosphite
Triethyl phosphate
Diethyl methylphosphonate
diethyl sodium phosphite
2-(5-methyl-2-phenyl-4-oxazolyl)methyl-5-benzofurancarboxaldehyde
Methyl 2-(diethoxyphosphoryl)acetate

DownStream

ethyl 3-(4-tert-butylphenyl)prop-2-enoate
Ethyl 3-(4-(trifluoromethyl)phenyl)acrylate
4-(Trifluoromethyl)benzoic acid
ethyl 2-diethoxyphosphoryl-3-trimethylsilylpropanoate
3-(3-PHENOXY-PHENYL)-PROPAN-1-OL
ethyl 1-diethoxyphosphorylcyclopropane-1-carboxylate
ethyl 2-diethoxyphosphorylpent-4-enoate
ethyl 2-diethoxyphosphoryl-2-(prop-2-enyl)pent-4-enoate
ethyl 6-chlorohex-2-enoate
ethyl 4,4-diethoxybut-2-enoate

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

"Carba" peptide bond surrogates. Different approaches to Gly-psi(CH2-CH2)-D,L-Xaa pseudo-dipeptide units.

Int. J. Pept. Protein Res. 39(3) , 273-7, (1992)

Racemic "carba" pseudo-dipeptide units such as Gly-psi(CH2-CH2)-D,L-Xaa were obtained either through the Horner-Emmons condensation of N-tert.-butyloxycarbonyl-beta alaninal with the appropriate subst...

J. Boutagy, R. Thomas

Chem. Rev. 74 , 87, (1974)

T. Minami, J. Motoyoshiya

Synthesis , 333, (1991)