Metasystox
Suppliers
Names
[ CAS No. ]:
867-27-6
[ Name ]:
Metasystox
[Synonym ]:
O-[2-(ethylsulfanyl)ethyl] O,O-dimethyl phosphorothioate
Methyl-demeton-O
O-2-ethylthioethyl O,O-dimethyl phosphorothioate
Demeton-S-methyl
O,O-Dimethyl O-ethylmercaptoethyl thiophosphate
O-[2-(ethylthio)ethyl] O,O-dimethyl phosphorothioate
Demeton-O-methyl
2-ethylsulfanylethoxy-dimethoxy-sulfanylidene-λ<sup>5</sup>-phosphane
methylmercaptophos
EINECS 212-758-1
Methyl-O-demeton
Chemical & Physical Properties
[ Density]:
1.207
[ Boiling Point ]:
89(0.02kPa)
[ Molecular Formula ]:
C6H15O3PS2
[ Molecular Weight ]:
230.28500
[ Flash Point ]:
112.1ºC
[ Exact Mass ]:
230.02000
[ PSA ]:
94.89000
[ LogP ]:
2.92400
[ Index of Refraction ]:
1.505
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TG1650000
- CHEMICAL NAME :
- Phosphorothioic acid, O-(2-(ethylthio)ethyl) O,O-dimethyl ester
- CAS REGISTRY NUMBER :
- 867-27-6
- BEILSTEIN REFERENCE NO. :
- 1707378
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H15-O3-P-S2
- MOLECULAR WEIGHT :
- 230.30
- WISWESSER LINE NOTATION :
- 2S2OPS&O1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 216 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 67,187,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 20 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(3),21,1963
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW MZUZA8 Meditsinskii Zhurnal Uzbekistana. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1957- Volume(issue)/page/year: (8),90,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 0.05 ppm (0.5 mg/m3);Skin JAN 1993
Safety Information
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
25
[ Safety Phrases ]:
24-36/37-45
[ RIDADR ]:
UN 3018
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)