5-(4-Amino-3-methoxybenzyl)-2,4-thiazolidinedione

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Names

[ CAS No. ]:
86733-81-5

[ Name ]:
5-(4-Amino-3-methoxybenzyl)-2,4-thiazolidinedione

Chemical & Physical Properties

[ Density]:
1.387g/cm3

[ Boiling Point ]:
484.9ºC at 760 mmHg

[ Molecular Formula ]:
C11H12N2O3S

[ Molecular Weight ]:
252.29000

[ Flash Point ]:
247ºC

[ Exact Mass ]:
252.05700

[ PSA ]:
106.72000

[ LogP ]:
2.08150

[ Index of Refraction ]:
1.642

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ5785000
CHEMICAL NAME :
2,4-Thiazolidinedione, 5-(4-amino-3-methoxybenzyl)-
CAS REGISTRY NUMBER :
86733-81-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H12-N2-O3-S
MOLECULAR WEIGHT :
252.31
WISWESSER LINE NOTATION :
TSVMVTJ E1R DZ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 31,560,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-(4-acetamido-3-methoxybenzyl)-2-iminothiazolidin-4-one
  • methyl 3-(4-acetamido-3-methoxyphenyl)-2-chloropropanoate
  • Acetamide,N-(4-amino-2-methoxyphenyl)-

DownStream

Related Compounds

  • 5-[(4-amino-3,5-dimethoxy-phenyl)methyl]pyrimidine-2,4-diamine
  • 5-[(4-amino-3-methoxyphenyl)methyl]pyrimidine-2,4-diamine
  • 5-(4-amino-3,5-dichlorophenyl)-3-prop-2-enyl-1,3-oxazolidin-2-one
  • 5-(4-amino-3-cyanophenyl)-1-methylpyrrole-2-carbonitrile
  • 5-(4-amino-3-fluorophenyl)-1-methylpyrrole-2-carbonitrile
  • 5-[[4-(3-phenylpropanoyl)phenyl]methyl]-1,3-thiazolidine-2,4-dione