2-Diethylaminoethylchloride Hydrochloride
Suppliers
Names
[ CAS No. ]:
869-24-9
[ Name ]:
2-Diethylaminoethylchloride Hydrochloride
[Synonym ]:
(β-Chloroethyl)diethylamine hydrochloride
β-(Diethylamino)ethyl chloride hydrochloride
Diethyl(β-chloroethyl)amine hydrochloride
2-Diethylamino ethylchloride HCL
2-Chloro-N,N-diethylethanamine hydrochloride (1:1)
MFCD00008385
β-Chloroethyldiethylamine hydrochloride
2-Diethylaminoethylchloride hydrochloride
Diethyl-β-chloroethylamine hydrochloride
Ethanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1)
N,N-Diethyl-β-chloroethylamine hydrochloride
EINECS 210-673-4
Amiodarone Impurity 8
Chemical & Physical Properties
[ Boiling Point ]:
255 °C(lit.)
[ Melting Point ]:
50-53 °C(lit.)
[ Molecular Formula ]:
C6H15Cl2N
[ Molecular Weight ]:
172.096
[ Flash Point ]:
186 °F
[ Exact Mass ]:
171.058151
[ PSA ]:
3.24000
[ LogP ]:
2.36900
[ Storage condition ]:
Poison room
[ Water Solubility ]:
2000 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YE1050000
- CHEMICAL NAME :
- Triethylamine, 2-chloro-, hydrochloride
- CAS REGISTRY NUMBER :
- 869-24-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 21
- MOLECULAR FORMULA :
- C6-H14-Cl-N.Cl-H
- MOLECULAR WEIGHT :
- 172.12
- WISWESSER LINE NOTATION :
- G2N2&2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 103 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 71 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 42 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 22 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,33,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7462 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4354 (estimated) No. of Female Employees: 729 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330-H315-H318-H335
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P280-P302 + P352 + P310-P304 + P340 + P310-P305 + P351 + P338 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn, T, Xi, T+
[ Risk Phrases ]:
R24/25;R26;R36/37/38
[ Safety Phrases ]:
S26-S36-S45-S36/37/39-S28A
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
DC2810000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29211980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29211980
Articles
Gig. Tr. Prof. Zabol. (2) , 54-6, (1985)
Contact Dermatitis 18(2) , 103-5, (1988)