(5-Chloro-2-iodophenyl)(2,6-difluorophenyl)methanone

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Names

[ CAS No. ]:
869365-97-9

[ Name ]:
(5-Chloro-2-iodophenyl)(2,6-difluorophenyl)methanone

[Synonym ]:
QC-8170
(5-CHLORO-2-IODOPHENYL)(2,6-DIFLUOROPHENYL)METHANONE
Methanone,(5-chloro-2-iodophenyl)(2,6-difluorophenyl)

Chemical & Physical Properties

[ Density]:
1.803g/cm3

[ Boiling Point ]:
433.54ºC at 760 mmHg

[ Molecular Formula ]:
C13H6ClF2IO

[ Molecular Weight ]:
378.54000

[ Flash Point ]:
215.998ºC

[ Exact Mass ]:
377.91200

[ PSA ]:
17.07000

[ LogP ]:
4.45380

[ Index of Refraction ]:
1.621

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
  • tert-butyl 4-chloro-2-(2,6-difluorobenzoyl)phenylcarbamate
  • 4-chloro-(n-boc)aniline 97
  • 2,6-Difluorobenzoyl chloride

DownStream

  • MLN8054
  • Alisertib (MLN8237)
  • (5-CHLORO-2-IODOPHENYL)(2-FLUORO-6-METHOXYPHENYL)METHANONE
  • [3-[4-Chloro-2-(2,6-difluorobenzoyl)phenyl]prop-2-ynyl]carbamic acid tert-butyl ester
  • 8-chloro-1-(2,6-difluorophenyl)-3,4-dihydro-2-benzazepin-5-one
  • TERT-BUTYL (3-(4-CHLORO-2-(2-FLUORO-6-METHOXYBENZOYL)PHENYL)PROP-2-YN-1-YL)CARBAMATE
  • (1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%