8-chloro-1-(2,6-difluorophenyl)-3,4-dihydro-2-benzazepin-5-one

Names

[ CAS No. ]:
869366-09-6

[ Name ]:
8-chloro-1-(2,6-difluorophenyl)-3,4-dihydro-2-benzazepin-5-one

[Synonym ]:
8-Chlor-4-aminochinolin
4-Amino-8-chlorchinolin
8-chloro-4-quinolylamine
8-chloranylquinolin-4-amine
4-Quinolinamine,8-chloro
8-chloro-4-quinolinamine
8-chloro-quinolin-4-ylamine
8-Chlor-[4]chinolylamin
8-chloro-1-(2,6-difluorophenyl)-3,4-dihydrobenzo[c]azepin-5-one
4-Amino-8-chloroquinoline
8-chloro-1-(2,6-difluorophenyl)-3H-benzo[c]azepin-5(4H)-one

Chemical & Physical Properties

[ Molecular Formula ]:
C16H10ClF2NO

[ Molecular Weight ]:
305.70700

[ Exact Mass ]:
305.04200

[ PSA ]:
29.43000

[ LogP ]:
3.47760

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • [3-[4-Chloro-2-(2,6-difluorobenzoyl)phenyl]prop-2-ynyl]carbamic acid tert-butyl ester
  • tert-butyl 4-chloro-2-(2,6-difluorobenzoyl)phenylcarbamate
  • (5-Chloro-2-iodophenyl)(2,6-difluorophenyl)methanone
  • (2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
  • 4-chloro-(n-boc)aniline 97
  • 2,6-Difluorobenzoyl chloride

DownStream

  • MLN8054

Related Compounds

  • N-[3-(Aminomethyl)-2-pyridinyl]-N-methyl-4-pyridineethanamine
  • 2-Methyl-5-[1-methylpyrazol-3-yl]pyridine
  • 3-Methyl-6-(4-(methylsulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide
  • 5-(6-(4-(Isopropylsulfonyl)phenyl)pyrazin-2-yl)-3-phenylisoxazole
  • 3-(Cyclopropyl(thieno[2,3-d]pyrimidin-4-yl)amino)propanenitrile
  • 1-Methyl-2-(2-methylcyclohexyl)benzene
  • Benzenecarbothioic acid, 2,5-difluoro-, hydrazide
  • N-cyclopropylazetidine-3-carboxamide
  • 4-Bromo-2-((4-fluorophenyl)sulfonyl)thiazole
  • n-Cyclopropyl-n-(1,5-dimethyl-1h-pyrazole-4-carbonyl)glycine
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