8-chloro-1-(2,6-difluorophenyl)-3,4-dihydro-2-benzazepin-5-one

Names

[ CAS No. ]:
869366-09-6

[ Name ]:
8-chloro-1-(2,6-difluorophenyl)-3,4-dihydro-2-benzazepin-5-one

[Synonym ]:
8-Chlor-4-aminochinolin
4-Amino-8-chlorchinolin
8-chloro-4-quinolylamine
8-chloranylquinolin-4-amine
4-Quinolinamine,8-chloro
8-chloro-4-quinolinamine
8-chloro-quinolin-4-ylamine
8-Chlor-[4]chinolylamin
8-chloro-1-(2,6-difluorophenyl)-3,4-dihydrobenzo[c]azepin-5-one
4-Amino-8-chloroquinoline
8-chloro-1-(2,6-difluorophenyl)-3H-benzo[c]azepin-5(4H)-one

Chemical & Physical Properties

[ Molecular Formula ]:
C16H10ClF2NO

[ Molecular Weight ]:
305.70700

[ Exact Mass ]:
305.04200

[ PSA ]:
29.43000

[ LogP ]:
3.47760

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • [3-[4-Chloro-2-(2,6-difluorobenzoyl)phenyl]prop-2-ynyl]carbamic acid tert-butyl ester
  • tert-butyl 4-chloro-2-(2,6-difluorobenzoyl)phenylcarbamate
  • (5-Chloro-2-iodophenyl)(2,6-difluorophenyl)methanone
  • (2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
  • 4-chloro-(n-boc)aniline 97
  • 2,6-Difluorobenzoyl chloride

DownStream

  • MLN8054

Related Compounds

  • 1-(2-Fluoropropan-2-yl)-3-hydroxycyclobutane-1-carboxylic acid
  • 3-(2-Fluoropropan-2-yl)oxolane-2,5-dione
  • 3-(Aminomethyl)-3-(4-methyl-1,3-thiazol-5-yl)cyclobutan-1-ol
  • O-[2-(2-nitrophenyl)propan-2-yl]hydroxylamine
  • 3-[(4-Methyl-1,3-thiazol-5-yl)oxy]propan-1-amine
  • 1-[2-(4-Methyl-1,3-thiazol-5-yl)propan-2-yl]cyclopropan-1-amine
  • 3-amino-2-(1-ethyl-1H-imidazol-5-yl)propan-1-ol
  • (2R)-1-(1-ethylcyclobutyl)propan-2-amine
  • Methyl 5-(4-amino-2-methylbutan-2-yl)thiophene-2-carboxylate
  • 3-[5-(Methoxycarbonyl)thiophen-2-yl]-3-methylbutanoic acid
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