Homatropine
Suppliers
Names
[ CAS No. ]:
87-00-3
[ Name ]:
Homatropine
[Synonym ]:
Omatropina [DCIT]
Homatropin
Homotropine
DL-mandelic acid-tropane-3endo-yl ester
Homoatropine
homatropine
Mandelyltropeine
Homatropine [BAN]
Methylhomatropinum
DL-Mandelsaeure-tropan-3endo-ylester
EINECS 201-716-8
homatropine hydrobromide
8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
Mandelytropeine
MFCD00067305
Chemical & Physical Properties
[ Density]:
1.21 g/cm3
[ Boiling Point ]:
403.3ºC
[ Melting Point ]:
100ºC
[ Molecular Formula ]:
C16H21NO3
[ Molecular Weight ]:
275.34300
[ Flash Point ]:
197.7ºC
[ Exact Mass ]:
275.15200
[ PSA ]:
49.77000
[ LogP ]:
1.82630
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM5600000
- CHEMICAL NAME :
- 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, mandelate (ester)
- CAS REGISTRY NUMBER :
- 87-00-3
- BEILSTEIN REFERENCE NO. :
- 0087959
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C16-H21-N-O3
- MOLECULAR WEIGHT :
- 275.38
- WISWESSER LINE NOTATION :
- T56 A ANTJ A1 GOVYQR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,156,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1307 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84350 No. of Facilities: 170 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2582 (estimated)
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%