2,6-Dichlorophenol

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Names

[ CAS No. ]:
87-65-0

[ Name ]:
2,6-Dichlorophenol

[Synonym ]:
2,6-Dichlor-phenol
EINECS 201-761-3
2,6-Dichlorfenol
2,6-Dichlorophenol
2,6-Cl2-C6H3OH
2,4,6-trichlorophenole
2,6-dichloro-phenol
Phenol, 2,6-dichloro-
HO-2,6-C6H3Cl2
Phenol,2,6-dichloro
2,6-Dichlorfenol [Czech]
RCRA waste no. U082
MFCD00002176
2.6-Dichlor-1-hydroxy-benzol
RCRA waste number U082

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
219.0±0.0 °C at 760 mmHg

[ Melting Point ]:
65 °C

[ Molecular Formula ]:
C6H4Cl2O

[ Molecular Weight ]:
163.001

[ Flash Point ]:
94.9±15.8 °C

[ Exact Mass ]:
161.963913

[ PSA ]:
20.23000

[ LogP ]:
2.61

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.594

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides.

[ Water Solubility ]:
<0.1 g/100 mL at 20 ºC

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SK8750000
CHEMICAL NAME :
Phenol, 2,6-dichloro-
CAS REGISTRY NUMBER :
87-65-0
BEILSTEIN REFERENCE NO. :
1447806
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C6-H4-Cl2-O
MOLECULAR WEIGHT :
163.00
WISWESSER LINE NOTATION :
QR BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,524,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,524,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,20,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2120 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 29,39,1985

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S27-S36/37/39-S37/39-S45-S36/37-S16

[ RIDADR ]:
UN 2020 6.1/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
SK8750000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2908199090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Chlorophenol
  • 3,5-Dichloro-4-hydroxybenzoic acid
  • Phenol
  • tert-butyl (2,6-dichlorophenoxy)dimethylsilane
  • 2,6-DICHLOROANISOL
  • 2,6-Dichlorobenzaldehyde
  • 2,2,6,6-Tetrachlorocyclohexanone
  • 1,2,4-Triazole
  • 2,4,6-Trichlorophenol

DownStream

  • 3-(2,6-DICHLOROPHENOXY)-1-PROPYNE
  • 3,5-Dichloro-4-hydroxybenzoic acid
  • 2,6-Dichloro-4-bromophenol
  • diisopropyl bicarbamate
  • nitrobenzene
  • 1,3-dichloro-2-(2,4-dichlorophenoxy)benzene
  • biphenol
  • Phenol
  • methyl 2-(2,6-dichlorophenoxy)acetate

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

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Related Compounds

  • 2,6-dichlorophenol)
  • 4--2,6-dichlorophenol
  • 2,6-dichlorophenol acetate
  • 3-bromo-2,6-dichlorophenol
  • 4-bromo-2,6-dichlorophenol
  • 4-Nitro-2,6-dichlorophenol
  • N-[2-[(1-Cyanocyclobutyl)-methylamino]-2-oxoethyl]-2,3-dihydro-1H-indene-5-carboxamide
  • I+/--Ethyl-2,3-dihydro-1H-indene-5-acetonitrile
  • 3-(1-propyl-1H-1,2,3,4-tetrazol-5-yl)propan-1-amine
  • N-(1-Cyanocyclobutyl)-2-[(3,5-dimethylphenyl)formamido]-N-methylacetamide
  • N-[(3-Chlorophenyl)(cyano)methyl]-2-[(3-methylphenyl)formamido]acetamide
  • [3-(4-Bromophenyl)-2,2-dimethylcyclopropyl]methanamine
  • 5-Phenyl-3-(4-prop-2-ynylpiperazin-1-yl)-1,2,4-oxadiazole
  • 2-(1H-indol-2-yl)-2-methylpropanal
  • (5-Chloro-2-nitrophenyl)methanethiol
  • 4-(6-Chloro-5-methyl-3-pyridyl)morpholine
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