2-Chloroethanamine hydrochloride

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Names

[ CAS No. ]:
870-24-6

[ Name ]:
2-Chloroethanamine hydrochloride

[Synonym ]:
2-Chloropropylamine HCL
β-Chloroethylamine hydrochloride
2-chloroethanamine hydrochloride
2-Chloroethylamine
2-Chloroethylazanium chloride
2-Chloroethylamine h
2-CHLOROETHYLAMINE HCL
MFCD00012887
CHLOROETHYLAMINE HYDROCHLORIDE
2-Chloroethylamine HCl anhyd.
EINECS 212-793-2
2-Chloroethylammonium chloride
1-amino-2-chloroethane hydrochloride
2-aminoethyl chloride hydrochloride
2-chloroethylamine monohydrochloride
2-Chlorethanaminhydrochlorid
2-Chloroethanamine hydrochloride (1:1)
Ethanamine, 2-chloro-, hydrochloride (1:1)

Chemical & Physical Properties

[ Density]:
1.038 g/cm3

[ Boiling Point ]:
108.9ºC at 760 mmHg

[ Melting Point ]:
140-150 °C(lit.)

[ Molecular Formula ]:
C2H7Cl2N

[ Molecular Weight ]:
115.990

[ Exact Mass ]:
114.995552

[ PSA ]:
26.02000

[ LogP ]:
1.68620

[ Index of Refraction ]:
1.427

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR1800000
CHEMICAL NAME :
Ethylamine, 2-chloro-, hydrochloride
CAS REGISTRY NUMBER :
870-24-6
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C2-H6-Cl-N.Cl-H
MOLECULAR WEIGHT :
116.00
WISWESSER LINE NOTATION :
Z2G &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2204 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia

MUTATION DATA

TYPE OF TEST :
Unscheduled DNA synthesis
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
100 umol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981

Safety Information

[ Symbol ]:

GHS05, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H341

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN3261

[ WGK Germany ]:
3

[ RTECS ]:
KR1800000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • β-Aminoethanol hydrochloride
  • Thionyl chloride
  • N,N-Dimethylformamide
  • 2-Aminoethanol
  • N-Hydroxyethylphthalimide
  • Aziridine
  • oxazolidinone
  • Hydrochloric acid
  • Toluene

DownStream

  • [2-(Pyridin-2-ylthio)ethyl]amine dihydrochloride
  • dechloroethylcyclophosphamide
  • oxazolidinone
  • 2-[(4-CHLOROPHENYL)THIO]ETHANAMINE
  • 3, 4-Dihydrobenzo[f][1, 4]thiazepin-5(2H)-one
  • Aminothiazoline
  • 2-(Diphenylphosphino)ethanamine
  • 2-(Pyridin-3-yl)-4,5-dihydrooxazole
  • N,N-BIS(2-CHLOROETHYL)-P-TOLUENESULFONAMIDE
  • (6R)-6-amino-1,4-thiazepan-5-one

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis of a carboxamide linked T*T dimer and its incorporation in oligonucleotides.

Nucleic Acids Res. 21 , 5179, (1993)

The condensation of 5'-O-protected 3'-O-(2-aminoethyl)thymidine with 1,2-dideoxy-1-thyminyl-beta-D-erythro-pentofuranuronic acid gives a T*T dimer with * representing a 3'-OCH2CH2NHC(O)-4' linkage con...

In the search for new anticancer drugs. XXIV: Synthesis and anticancer activity of amino acids and dipeptides containing the 2-chloroethyl- and [N'-(2-chloroethyl)-N'-nitroso]-aminocarbonyl groups.

J. Pharm. Sci. 82 , 1, (1993)

A series of L,L- (42, 44, 46, and 60) and D,D- (43, 45, 47, and 61) dipeptide derivatives composed of phenylglycine, phenylalanine, homophenylalanine, and valine and containing a 2-chloroethylamino gr...


More Articles

Related Compounds

  • N-BENZYL-2-CHLOROETHANAMINE HYDROCHLORIDE
  • N,N-Dibenzyl-2-chloroethanamine hydrochloride (1:1)
  • N-(1-benzothiophen-3-ylmethyl)-N-benzyl-2-chloroethanamine hydrochloride
  • N-benzyl-N-[(5-bromo-1-benzothiophen-3-yl)methyl]-2-chloroethanamine hydrochloride
  • N-(2-bromoethyl)-2-chloroethanamine,hydrochloride
  • N-[bis(4-fluorophenyl)methyl]-2-chloroethanamine,hydrochloride