Trametinib (GSK1120212)

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Names

[ CAS No. ]:
871700-17-3

[ Name ]:
Trametinib (GSK1120212)

[Synonym ]:
UNII-33E86K87QN
GSK 1120212
GSK-1120212
Mekinist
N-(3-{3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide
Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
GSK1120212
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
JTP74057
Trametinib

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C26H23FIN5O4

[ Molecular Weight ]:
615.395

[ Exact Mass ]:
615.077881

[ PSA ]:
110.62000

[ LogP ]:
2.68

[ Index of Refraction ]:
1.734

[ Storage condition ]:
2-8°C

Safety Information

[ Safety Phrases ]:
24/25

[ HS Code ]:
29339900

Related Compounds

  • Trametinib-13C,d3
  • Trametinib (DMSO solvate)
  • 4-{[(1-methyl-1H-pyrazol-4-yl)methyl]amino}butan-1-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 3-Pyridinecarbonitrile, 2-(6-amino-1H-indazol-1-yl)-
  • ethyl 2-amino-3-(4-chloro-3-methyl-1H-pyrazol-1-yl)-2-methylpropanoate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde