Trametinib (GSK1120212)

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Names

[ CAS No. ]:
871700-17-3

[ Name ]:
Trametinib (GSK1120212)

[Synonym ]:
UNII-33E86K87QN
GSK 1120212
GSK-1120212
Mekinist
N-(3-{3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide
Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
GSK1120212
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
JTP74057
Trametinib

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C26H23FIN5O4

[ Molecular Weight ]:
615.395

[ Exact Mass ]:
615.077881

[ PSA ]:
110.62000

[ LogP ]:
2.68

[ Index of Refraction ]:
1.734

[ Storage condition ]:
2-8°C

Safety Information

[ Safety Phrases ]:
24/25

[ HS Code ]:
29339900

Related Compounds

  • Trametinib-13C,d3
  • Trametinib (DMSO solvate)
  • 3-{[3-(Methylsulfanyl)phenyl]methyl}pyrrolidin-3-ol
  • 4-(4-Fluorophenyl)pent-2-en-1-amine
  • tert-butyl N-{5-[2-(1-hydroxycyclopropyl)ethyl]-2-methylphenyl}carbamate
  • tert-butyl N-[2-amino-3-(3-chloro-2,6-difluorophenyl)propyl]carbamate
  • 2-Bromo-1-(5-chloropyridin-2-yl)ethan-1-ol
  • tert-butyl 3-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]morpholine-4-carboxylate
  • Methyl 2-chloro-4-(2-isocyanatoethyl)benzoate
  • 2-(2-{[(Tert-butoxy)carbonyl]amino}-4,5-dimethoxyphenyl)acetic acid
  • 1-(5-Bromo-2-cyclopropylpyrimidin-4-yl)-2,2-difluoroethan-1-amine
  • 1-[1-(2-Bromo-1,3-thiazol-4-yl)cyclopropyl]ethan-1-one
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