Dihydrotanshinone I

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Names

[ Name ]:
Dihydrotanshinone I

[Synonym ]:
1,6-Dimethyl-1,2-dihydrophenanthro[1,2-b]furan-10,11-dione
1,2-dihydrotanshinone
Tanshinone I,dihydro
dihydrotanshinone 1
1,2-dihydrotanshinone I
15,16-dihydrotanshinone I
Phenanthro[1,2-b]furan-10,11-dione, 1,2-dihydro-1,6-dimethyl-
Dihydrotanshinone I

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
479.2±45.0 °C at 760 mmHg

[ Melting Point ]:
214.0 to 218.0 °C

[ Molecular Formula ]:
C₁₈H₁₄O₃

[ Molecular Weight ]:
278.302

[ Flash Point ]:
214.9±28.8 °C

[ Exact Mass ]:
278.094299

[ PSA ]:
43.37000

[ LogP ]:
3.90

[ Appearance of Characters ]:
red

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.671

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
ethanol: soluble1mg/mL, clear, orange to red

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
22-50

[ Safety Phrases ]:
61

[ RIDADR ]:
UN 3077 9 / PGIII

[ RTECS ]:
SF8282630

Articles

Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.

Sci. Rep. 5 , 16478, (2015)

Post-transcriptional regulation is an essential determinant of gene expression programs in physiological and pathological conditions. HuR is a RNA-binding protein that orchestrates the stabilization a...

Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage.

Fitoterapia 83 , 1666-1674, (2012)

We observed neuroprotective effects of five major lipophilic diterpenes derived from Danshen (Radix Salvia miltiorrhiza) extract, such as cryptotanshinone (CTs), dihydrotanshinone I (DTsI), tanshinone...

Modeling gradient elution in countercurrent chromatography: efficient separation of tanshinones from Salvia miltiorrhiza Bunge.

J. Sep. Sci. 35 , 964-976, (2012)

Countercurrent chromatography (CCC) is a support-free liquid-liquid chromatography using centrifugal fields to hold the liquid stationary phase. CCC has been widely applied in the separation of variou...

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