Infigratinib (BGJ398)

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Names

[ CAS No. ]:
872511-34-7

[ Name ]:
Infigratinib (BGJ398)

[Synonym ]:
BGJ-398
UNII-A4055ME1VK
BGJ398
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)-1-methylurea
infigratinib
Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-
NVP-BGJ398
3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylurea

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
747.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H31Cl2N7O3

[ Molecular Weight ]:
560.475

[ Flash Point ]:
406.1±32.9 °C

[ Exact Mass ]:
559.186523

[ PSA ]:
98.58000

[ LogP ]:
5.03

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.654

[ Storage condition ]:
-20°C


Related Compounds

  • NVP-BGJ398 (phosphate)
  • Tert-butyl 3-(2-bromoethynyl)-3-hydroxypiperidine-1-carboxylate
  • (9H-fluoren-9-yl)methyl 4-(4-hydroxybenzoyl)piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-[1-(2-hydroxyethyl)-3-(4-propylphenyl)-1H-pyrazol-5-yl]carbamate
  • (9H-fluoren-9-yl)methyl N-[1-(2-hydroxyethyl)-3-(3-methoxyphenyl)-1H-pyrazol-5-yl]carbamate
  • (9H-fluoren-9-yl)methyl N-[1-(2-hydroxyethyl)-3-(2-methylfuran-3-yl)-1H-pyrazol-5-yl]carbamate
  • (9H-fluoren-9-yl)methyl N-(2-hydroxyethyl)-N-(pyridin-2-yl)carbamate
  • (9H-fluoren-9-yl)methyl (1R,5S,6R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
  • (9H-fluoren-9-yl)methyl N-heptyl-N-(3-hydroxypropyl)carbamate
  • (9H-fluoren-9-yl)methyl N-[(3-hydroxy-4-methoxyphenyl)methyl]carbamate
  • (9H-fluoren-9-yl)methyl N-(2-hydroxy-2-phenylethyl)-N-(propan-2-yl)carbamate
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