2,6-dichloro-4-(o-tolyl)nicotinonitrile

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Names

[ CAS No. ]:
873443-66-4

[ Name ]:
2,6-dichloro-4-(o-tolyl)nicotinonitrile

[Synonym ]:
3-PYRIDINECARBONITRILE,2,6-DICHLORO-4-(2-METHYLPHENYL)
3-cyano-2,6-dichloro-4-(2-methylphenyl)pyridine

Chemical & Physical Properties

[ Boiling Point ]:
399.6±42.0°C at 760 mmHg

[ Molecular Formula ]:
C13H8Cl2N2

[ Molecular Weight ]:
263.12200

[ Exact Mass ]:
262.00600

[ PSA ]:
36.68000

[ LogP ]:
4.23548

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1',2',3',4'-tetrahydro-5'-cyano-6'-hydroxy-4'-(2-methylphenyl)-2'-oxo-1,3'-bipyridinium, zwitter ion
  • 2-Methylbenzaldehyde
  • 2-Propenoic acid, 2-cyano-3-(2-methylphenyl)-, methyl ester

DownStream

  • 6-(4-Methylpiperazin-1-yl)-4-(2-methylphenyl)nicotinamide
  • 4-(2-methylphenyl)-6-morpholin-4-ylpyridine-3-carboxamide
  • Netupitant
  • Befetupitant
  • 2-chloro-4-(2-methylphenyl)-6-morpholin-4-ylpyridine-3-carbonitrile

Related Compounds

  • 2,6-dimethyl-4-o-tolyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
  • 2,6-Dichloro-4-(trifluoromethyl)nicotinonitrile
  • 2,6-dichloro-4-(chloromethyl)nicotinonitrile
  • 2,6-Dichloro-4-isopropylnicotinonitrile
  • {2,6-dichloro-4-[(phenylsulfinyl)methyl]pyridin-3-yl}(4-methylphenyl)methanone
  • 2,6-dichloro-4,5-dimethylpyridine-3-carbonitrile
  • N-(3-fluorophenyl)-2-[2-(phenylamino)-1,3-thiazol-4-yl]acetamide
  • 2-chloro-6-fluoro-N-(2-{7-methoxy-1,8-dioxo-1H,2H,3H,4H,8H-pyrido[1,2-a]pyrazin-2-yl}ethyl)benzamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)phenoxy]-N-[3-(4-morpholinyl)propyl]acetamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-Methyl-5-phenyl-octahydropyrrolo[3,4-c]pyrrole